The skeleton is a dynamic organ that is constantly remodeled. Proteins secreted from bone
cells, namely osteoblasts, osteocytes, and osteoclasts exert regulation on …

Disruption of bone remodelling by diseases such as osteoporosis results in an imbalance
between bone formation by osteoblasts and resorption by osteoclasts. Research into these …

Much has been written recently on osteoclast biology, but this cell type still astonishes
scientists with its multifaceted functions and unique properties. The last three decades have …

Bone remodeling is essential for the repair and replacement of damaged and old bone. The
major principle underlying this process is that osteoclast-mediated resorption of a quantum …

Some biomaterials are osteoinductive, that is, they are able to trigger the osteogenic process
by inducing the differentiation of mesenchymal stem cells to the osteogenic lineage …

Background The article provides the scientific documentation for the 3D animated film–
“Osseointegration–Communication of cells”. Aim The aim of this article and of the film is to …

Under most conditions, resorbed bone is nearly precisely replaced in location and amount
by new bone. Thus, it has long been recognized that bone loss through osteoclast-mediated …

Angiogenesis plays an important role in physiological bone growth and remodeling, as well
as in pathological bone disorders such as fracture repair, osteonecrosis, and tumor …

There is an urgent need of synthetic bone grafts with enhanced osteogenic capacity. This
can be achieved by combining biomaterials with exogenous growth factors, which however …

In response to mechanical forces and the aging process, bone in the adult skeleton is
continuously remodeled by a process in which old and damaged bone is removed by bone …