Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

The excessive inflammatory response of macrophages plays a vital role in the pathogenesis
of various diseases. The dynamic metabolic alterations in macrophages, including amino …

The resistance and immune escape of methicillin-resistant Staphylococcus aureus (MRSA)
biofilms cause recalcitrant infections. Here, we design a targeting and synergizing cascade …

Significance: Persulfides/polysulfides are sulfur-catenated molecular species (ie, R-Sn-R′,
n> 2; R-Sn-H, n> 1, with R= cysteine, glutathione, and proteins), such as cysteine persulfide …

For decades, the major focus of redox biology has been oxygen, the most abundant element
on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial …

The infected host deploys generalized oxidative stress caused by small inorganic reactive
molecules as antibacterial weapons. An emerging consensus is that hydrogen sulfide (H 2 …

Viruses influence the fate of nutrients and human health by killing microorganisms and
altering metabolic processes. Organosulfur metabolism and biologically derived hydrogen …

The prevalence of methicillin-resitant Staphylococcus aureus (MRSA) in hospitals and the
community poses an increasing health burden, which requires the discovery of alternative …

Low molecular weight (LMW) thiols play an important role as thiol-cofactors for many
enzymes and are crucial to maintain the reduced state of the cytoplasm. Most Gram-negative …

Cysteine persulfide and cysteine polysulfides are cysteine derivatives having sulfane sulfur
atoms bound to cysteine thiol. Accumulating evidence has suggested that cysteine …