[HTML][HTML] The immunomodulatory effects of probiotics and azithromycin in dextran sodium sulfate-induced ulcerative colitis in rats via TLR4-NF-κB and p38-MAPK …

SE Elkholy, SA Maher, NR Abd El-Hamid… - Biomedicine & …, 2023 - Elsevier
Ulcerative colitis (UC), a chronic autoimmune disease of the gut with a relapsing and
remitting nature, considers a major health-care problem. DSS is a well-studied …

Cardioprotective and renoprotective effects of venlafaxine on cisplatin-induced cardiotoxicity and nephrotoxicity in rats

MIM Ali, S Imbaby, HEK Arafat, SA Maher, E Kolieb… - Life sciences, 2023 - Elsevier
Aim The current work aims to demonstrate the potential defensive function of venlafaxine
(VLF) in cardiotoxicity and nephrotoxicity caused by cisplatin (CP), that could be by …

Stattic ameliorates the cecal ligation and puncture-induced cardiac injury in septic mice via IL-6-gp130-STAT3 signaling pathway

S Imbaby, Y Hattori - Life Sciences, 2023 - Elsevier
Aim Sepsis-induced cardiac dysfunction is the leading cause of higher morbidity and
mortality with poor prognosis in septic patients. Our recent previous investigation provides …

[HTML][HTML] Nitazoxanide reduces inflammation and bone erosion in mice with collagen-induced arthritis via inhibiting the JAK2/STAT3 and NF-κB pathways in fibroblast …

C Li, F Wang, Y Han, J Zhai, Y Jin, R Liu, Y Niu… - Biomedicine & …, 2024 - Elsevier
Highlights•NTZ dose-dependently inhibits the proliferation, migration and invasion of RA-
FLS.•NTZ prevents cell cycle progression and inflammatory cytokines mRNA …

Arabinose confers protection against intestinal injury by improving integrity of intestinal mucosal barrier

M Xu, F Shi, Y Gao, S Han, C Huang, Q Hou… - International …, 2024 - Elsevier
There is a growing amount of research that highlights the significant involvement of
metabolic imbalance and the inflammatory response in the advancement of colitis …

Wuling capsule modulates macrophage polarization by inhibiting the TLR4-NF-κB signaling pathway to relieve liver fibrosis

S Ren, R Zhou, Z Tang, Z Song, N Li, X Shi… - International …, 2024 - Elsevier
Background and purpose Wuling capsule (WL) has good efficacy in the clinical treatment of
chronic hepatitis B and liver injury. Liver fibrosis is a common pathological feature of chronic …

Protective effects of functional Nano-Selenium supplementation on spleen injury through regulation of p38 MAPK and NF-κB protein expression

R Xiang, X Xiao, J Liu, Z Guo, H He, X Wang… - International …, 2024 - Elsevier
Selenium (Se) is a trace element necessary for humans to maintain normal physiological
activities, and Se deficiency may lead to splenic injury, while Se supplementation can …

[HTML][HTML] miR-29b-1-5p exacerbates myocardial injury induced by sepsis in a mouse model by targeting TERF2: miR-29b-1-5p/TERF2 affect myocardial injury

Y Jiang, J Xu, H Zeng, Z Lin, Q Yi, J Guo… - Acta Biochimica et …, 2024 - ncbi.nlm.nih.gov
Myocardial damage is a critical complication and a significant contributor to mortality in
sepsis. MicroRNAs (miRNAs) have emerged as key players in sepsis pathogenesis. In this …

Expression of norA, norB and norC efflux pump genes mediating fluoroquinolones resistance in MRSA isolates

AB Hamady, NM Abd El-Fadeal, S Imbaby… - The Journal of Infection …, 2024 - jidc.org
Introduction: Although fluoroquinolones are used to treat methicillin-resistant
Staphylococcus aureus (MRSA)-induced infections, acquisition of antibiotic resistance by …