RNA-binding proteins (RBPs) are crucial regulators of gene expression, often composed of
defined domains interspersed with flexible, intrinsically disordered regions. Determining the …

The review describes the application of nuclear magnetic resonance (NMR) spectroscopy to
study kinetics of folding, refolding and aggregation of proteins, RNA and DNA. Time …

Chemical exchange saturation transfer (CEST) enhances solution-state NMR signals of
labile and otherwise invisible chemical sites, by indirectly detecting their signatures as a …

The nuclear Overhauser effect (NOE) is one of NMR spectroscopy's most important and
versatile parameters. NOE is routinely utilized to determine the structures of medium-to-large …

Multidimensional TOCSY and NOESY are central experiments in chemical and biophysical
NMR. Limited efficiencies are an intrinsic downside of these methods, particularly when …

Glycan structures are often stabilized by a repertoire of hydrogen-bonded donor/acceptor
groups, revealing longer-lived structures that could represent biologically relevant …

Protein and peptide interactions are characterized in the liquid state by multidimensional
NMR spectroscopy experiments, which can take hours to record. We show that starting from …

Both in spectroscopy and imaging, t 1-noise arising from instabilities such as temperature
alterations, field-related frequency drifts, electronic and sample-spinning instabilities, or …

Abstract 2D NOESY plays a central role in structural NMR spectroscopy. We have recently
discussed methods that rely on solvent‐driven exchanges to enhance NOE correlations …

A wide variety of nuclear magnetic resonance experiments rely on the prediction and
analysis of relaxation processes. Recently, innovative approaches have been introduced …