History of mankind is regarded as struggle against infectious diseases. Rather than
observing the withering away of bacterial diseases, antibiotic resistance has emerged as a …

Emergence of antimicrobial resistance (AMR) in cultured fishes is one of the major
challenges faced in aquaculture. The high prevalence of bacterial infections in fishes leads …

Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …

As recently indiscriminate abuse of existing antibiotics in both clinical and veterinary
treatment leads to proliferation of antibiotic resistance in microbes and poses a dilemma for …

Aminoglycosides have been an essential component of the armamentarium in the treatment
of life-threatening infections. Unfortunately, their efficacy has been reduced by the surge and …

Antibiotics were one of the great discoveries of the 20th century. However, resistance
appeared even in the earliest years of the antibiotic era. Antibiotic resistance continues to …

Integrons are assembly platforms—DNA elements that acquire open reading frames
embedded in exogenous gene cassettes and convert them to functional genes by ensuring …

Inland aquaculture contributed by three major fish groups, including carps, tilapias, and
catfish plays a vital role in global food security and nutrition, particularly in low and middle …

Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs)
embedded in gene cassette units and convert them to functional genes by ensuring their …

Gene cassettes are small mobile elements, consisting of little more than a single gene and
recombination site, which are captured by larger elements called integrons. Several …