The biological detoxification of deoxynivalenol: A review

Y Yao, M Long - Food and Chemical Toxicology, 2020 - Elsevier
Deoxynivalenol (DON), which is one of the most common mycotoxins produced by Fusarium
species, is often found known to contaminated food and feed all around the world. It usually …

Fungal toxins and host immune responses

R Brown, E Priest, JR Naglik… - Frontiers in microbiology, 2021 - frontiersin.org
Fungi are ubiquitous organisms that thrive in diverse natural environments including soils,
plants, animals, and the human body. In response to warmth, humidity, and moisture, certain …

Deoxynivalenol, gut microbiota and immunotoxicity: A potential approach?

Y Liao, Z Peng, L Chen, AK Nüssler, L Liu… - Food and Chemical …, 2018 - Elsevier
Deoxynivalenol (DON, vomitoxin) is the most frequent mycotoxin in grains and grain
products. DON contamination in fodder and food is a serious threat for health, since it …

Aflatoxin B1 and Epstein–Barr virus-induced CCL22 expression stimulates B cell infection

MA Maroui, GA Odongo, L Mundo… - Proceedings of the …, 2024 - National Acad Sciences
Epstein–Barr Virus (EBV) infects more than 90% of the adult population worldwide. EBV
infection is associated with Burkitt lymphoma (BL) though alone is not sufficient to induce …

Deoxynivalenol induces inflammation in IPEC-J2 cells by activating P38 Mapk and Erk1/2

H Zhang, X Deng, C Zhou, W Wu, H Zhang - Toxins, 2020 - mdpi.com
Fusarium-derived mycotoxin deoxynivalenol (DON) usually induces diarrhea, vomiting and
gastrointestinal inflammation. We studied the cytotoxic effect of DON on porcine small …

[HTML][HTML] Deoxynivalenol increases pro-inflammatory cytokine secretion and reduces primary bile acid transport in an inflamed intestinal in vitro co-culture model

J Wang, W Bakker, L de Haan… - Food Research …, 2023 - Elsevier
The fungal secondary metabolite deoxynivalenol (DON) that can contaminate cereal-based
food products not only induces inflammation but also reduces bile acid absorption by a …

Evaluation of the cytotoxic properties, gene expression profiles and secondary signalling responses of cultured cells exposed to fumonisin B1, deoxynivalenol and …

JF Wentzel, MJ Lombard, LH Du Plessis… - Archives of …, 2017 - Springer
Mycotoxins are toxic secondary metabolites produced by a range of fungi and are common
contaminants of agricultural crops. These toxins are chemically diverse and structurally …

The food contaminants nivalenol and deoxynivalenol induce inflammation in intestinal epithelial cells by regulating reactive oxygen species release

S Adesso, G Autore, A Quaroni, A Popolo, L Severino… - Nutrients, 2017 - mdpi.com
Fusarium mycotoxins are fungal metabolites whose ability to affect cereal grains as multi-
contaminants is progressively increasing. The trichothecene mycotoxins nivalenol (NIV) and …

The role of JAK2/STAT3 pathway in non-cytotoxic concentrations of DON-induced aggravation of inflammatory response in IL-10 deficient RAW264. 7 cells

J Zeng, Z Lin, J Tang, X Chen, K Huang… - Food and Chemical …, 2024 - Elsevier
Deoxynivalenol (DON) as a mycotoxin was commonly found in food and cereals which can
affect immune function and inflammatory response. The majority of foods contain DON at …

From ribosome to ribotoxins: Understanding the toxicity of deoxynivalenol and Shiga toxin, two food borne toxins

M Garofalo, D Payros, F Taieb, E Oswald… - Critical Reviews in …, 2023 - Taylor & Francis
Ribosomes that synthesize proteins are among the most central and evolutionarily
conserved organelles. Given the key role of proteins in cellular functions, prokaryotic and …