Nowadays, heterocyclic compounds act as a scaffold and are the backbone of medicinal
chemistry. Among all of the heterocyclic scaffolds, 1, 4-Dihydropyridine (1, 4-DHP) is one of …

Over the past two decades, polyoxometalates (POM) have received considerable attention
as solid catalysts, due to their unique physicochemical characteristics, since, first, they have …

Experimental and theoretical investigation of the anti-hypertensive activity of novel 2-[N-(4-
methylbenzenesulfonyl)-1-phenylformamido]-N-(4-nitrophenyl)-3-phenylpropenamide …

Amlodipine besylate (AMB) is a synthetic dihydropyridine calcium channel blocker with
antihypertensive and anti-anginal effects. Quantum computational investigations on AMB …

AlCl3-loaded ZnO nanoparticles have been explored as an efficient catalyst for 1, 4-
dihydropyridine synthesis under ambient temperature and solvent-free conditions. For this …

Voltage-gated calcium channels (VGCCs) manage the electrical signaling of cells by
allowing the selective-diffusion of calcium ions in response to the changes in the cellular …

Beta-Hydroxysteroid dehydrogenase-1 (11β-HSD1) inhibitors are one of the emerging
classes of molecules to fight against diabetic complications. A novel series of 4-(1 …

The aim of the present study is the synthesis of CuI nanoparticles (CuI Nps) through a green
route using red cabbage extract. X-ray diffraction (XRD) analysis confirmed the crystalline …

The present study, we design and synthesize the novel dihydropyridine derivatives, ie, 3
(ae) and 5 (ae) and evaluated, anticonvulsant activity. Initially due to the lacuna of LCC, we …

Amlodipine, a second-generation calcium channel blocker, exhibits documented anti-
inflammatory potential. Thereby, present investigation was accomplished with an aim to …