[HTML][HTML] Nanoscale self-assembly for therapeutic delivery

S Yadav, AK Sharma, P Kumar - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Self-assembly is the process of association of individual units of a material into highly
arranged/ordered structures/patterns. It imparts unique properties to both inorganic and …

[HTML][HTML] Nanosystems as vehicles for the delivery of antimicrobial peptides (AMPs)

Á Martin-Serrano, R Gómez, P Ortega, FJ de la Mata - Pharmaceutics, 2019 - mdpi.com
Recently, antimicrobial peptides (AMPs), also called host defence peptides (HDPs), are
attracting great interest, as they are a highly viable alternative in the search of new …

[HTML][HTML] Recent progress and advances of multi-stimuli-responsive dendrimers in drug delivery for cancer treatment

NTT Le, TNQ Nguyen, VD Cao, DT Hoang, VC Ngo… - Pharmaceutics, 2019 - mdpi.com
Despite the fact that nanocarriers as drug delivery systems overcome the limitation of
chemotherapy, the leakage of encapsulated drugs during the delivery process to the target …

Dendrimer-based delivery of macromolecules for the treatment of brain tumor

H Choudhury, M Pandey, R Mohgan, JSJ Jong… - Biomaterials …, 2022 - Elsevier
Brain tumor represents the most lethal form of cancer with the highest mortality and morbidity
rates irrespective of age and sex. Advancements in macromolecule-based therapy (such as …

[HTML][HTML] Dendrimer-mediated delivery of DNA and RNA vaccines

LA Kisakova, EK Apartsin, LF Nizolenko, LI Karpenko - Pharmaceutics, 2023 - mdpi.com
DNA and RNA vaccines (nucleic acid-based vaccines) are a promising platform for vaccine
development. The first mRNA vaccines (Moderna and Pfizer/BioNTech) were approved in …

Emerging strategies and therapeutic innovations for combating drug resistance in Staphylococcus aureus strains: A comprehensive review

M Gopikrishnan, S Haryini - Journal of Basic Microbiology, 2024 - Wiley Online Library
In recent years, antibiotic therapy has encountered significant challenges due to the rapid
emergence of multidrug resistance among bacteria responsible for life‐threatening …

[HTML][HTML] In vitro validation of the therapeutic potential of dendrimer-based nanoformulations against tumor stem cells

N Knauer, V Arkhipova, G Li, M Hewera… - International Journal of …, 2022 - mdpi.com
Tumor cells with stem cell properties are considered to play major roles in promoting the
development and malignant behavior of aggressive cancers. Therapeutic strategies that …

[HTML][HTML] Cationic polymers for the delivery of the Ebola DNA vaccine encoding artificial T-cell immunogen

LI Karpenko, EK Apartsin, SG Dudko, EV Starostina… - Vaccines, 2020 - mdpi.com
Background: According to current data, an effective Ebola virus vaccine should induce both
humoral and T-cell immunity. In this work, we focused our efforts on methods for delivering …

[HTML][HTML] The present and future role of microfluidics for protein and peptide-based therapeutics and diagnostics

E Weaver, S Uddin, DK Cole, A Hooker, DA Lamprou - Applied Sciences, 2021 - mdpi.com
The implementation of peptide-based molecules within the medical field has vast potential,
owing to their unique nature and predictable physicochemical profiles. However, peptide …

[HTML][HTML] Neglected zoonotic diseases: Advances in the development of cell-penetrating and antimicrobial peptides against leishmaniosis and Chagas disease

SM Robledo, S Pérez-Silanes, C Fernández-Rubio… - Pathogens, 2023 - mdpi.com
In 2020, the WHO established the road map for neglected tropical diseases 2021–2030,
which aims to control and eradicate 20 diseases, including leishmaniosis and Chagas …