Designer exosomes: a new platform for biotechnology therapeutics

D Jafari, S Shajari, R Jafari, N Mardi, H Gomari, F Ganji… - BioDrugs, 2020 - Springer
Desirable features of exosomes have made them a suitable manipulative platform for
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …

Recent advances in diagnostic approaches for epstein–barr virus

MAH Abusalah, SH Gan, MAI Al-Hatamleh, AA Irekeola… - Pathogens, 2020 - mdpi.com
Epstein–Barr virus (EBV) is the causative agent of many diseases including infectious
mononucleosis (IM), and it is associated with different subtypes of lymphoma, sarcoma and …

Key gaps in the knowledge of the porcine respiratory reproductive syndrome virus (PRRSV)

S Montaner-Tarbes, HA Del Portillo… - Frontiers in veterinary …, 2019 - frontiersin.org
The porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
important swine diseases in the world. It is causing an enormous economic burden due to …

Extracellular vesicles in cancer nanomedicine

VV Tarasov, AA Svistunov, VN Chubarev… - Seminars in cancer …, 2021 - Elsevier
To date, a lot of nanotechnological optitions are available for targeted drug delivery.
Extracellular vesicles (EVs) are membrane structures that cells use for storage, transport …

Multifunctional role of exosomes in viral diseases: From transmission to diagnosis and therapy

P Chaudhari, V Ghate, M Nampoothiri, S Lewis - Cellular signalling, 2022 - Elsevier
Efforts to discover antiviral drugs and diagnostic platforms have intensified to an
unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles …

A state-of-the-art review of the recent advances in exosome isolation and detection methods in viral infection

A Gorgzadeh, A Nazari, A Ali Ehsan Ismaeel… - Virology Journal, 2024 - Springer
Abstract Proteins, RNA, DNA, lipids, and carbohydrates are only some of the molecular
components found in exosomes released by tumor cells. They play an essential role in …

Prokaryotic microvesicles Ortholog of eukaryotic extracellular vesicles in biomedical fields

H Mobarak, F Javid, MT Narmi, N Mardi… - Cell Communication and …, 2024 - Springer
Every single cell can communicate with other cells in a paracrine manner via the production
of nano-sized extracellular vesicles. This phenomenon is conserved between prokaryotic …

Ras and exosome signaling

RE Sexton, G Mpilla, S Kim, PA Philip… - Seminars in cancer biology, 2019 - Elsevier
Ras gene (HRAS, NRAS, and KRAS) has been observed to be mutated and hyper-activated
in a significant proportion of cancers. However, mutant Ras remains a challenging …

Extracellular vesicles from human umbilical cord mesenchymal stem cells prevent steroid-induced avascular necrosis of the femoral head via the PI3K/AKT pathway

P Peng, XZ Wang, C Qiu, W Zheng, H Zhang - Food and Chemical …, 2023 - Elsevier
Extracellular vesicles (EVs) secreted by human umbilical cord mesenchymal stem cells
(hucMSC) have excellent therapeutic potential for many diseases. The aim of this study was …

The function and therapeutic potential of Epstein-Barr virus-encoded microRNAs in cancer

M Wang, B Gu, X Chen, Y Wang, P Li… - Molecular Therapy-Nucleic …, 2019 - cell.com
Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus that infects over 90% of the
global population. EBV is considered a contributory factor in a variety of malignancies …