Filamentous phages: masters of a microbial sharing economy

ID Hay, T Lithgow - EMBO reports, 2019 - embopress.org
Abstract Bacteriophage (“bacteria eaters”) or phage is the collective term for viruses that
infect bacteria. While most phages are pathogens that kill their bacterial hosts, the …

The structure and mechanism of the bacterial type II secretion system

S Naskar, M Hohl, M Tassinari… - Molecular …, 2021 - Wiley Online Library
The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …

Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin

J Hu, LJ Worrall, C Hong, M Vuckovic… - Nature …, 2018 - nature.com
The bacterial type III secretion system, or injectisome, is a syringe shaped nanomachine
essential for the virulence of many disease causing Gram-negative bacteria. At the core of …

Assembly mechanism of a Tad secretion system secretin-pilotin complex

M Tassinari, M Rudzite, A Filloux, HH Low - Nature Communications, 2023 - nature.com
The bacterial T ight ad herence S ecretion S ystem (TadSS) assembles surface pili that drive
cell adherence, biofilm formation and bacterial predation. The structure and mechanism of …

T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly

J Hu, LJ Worrall, M Vuckovic, C Hong, W Deng… - Nature …, 2019 - nature.com
The bacterial injectisome is a syringe-shaped macromolecular nanomachine utilized by
many pathogenic Gram-negative bacteria, including the causative agents of plague, typhoid …

Architecture, function, and substrates of the type II secretion system

KV Korotkov, M Sandkvist - EcoSal Plus, 2019 - Am Soc Microbiol
The type II secretion system (T2SS) delivers toxins and a range of hydrolytic enzymes,
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …

Secretory molecules from secretion systems fine-tune the host-beneficial bacteria (PGPRs) interaction

G Gupta, PS Chauhan, PN Jha, RK Verma… - Frontiers in …, 2024 - frontiersin.org
Numerous bacterial species associate with plants through commensal, mutualistic, or
parasitic association, affecting host physiology and health. The mechanism for such …

Phage selection drives resistance–virulence trade-offs in Ralstonia solanacearum plant-pathogenic bacterium irrespective of the growth temperature

J Wang, X Wang, K Yang, C Lu, B Fields, Y Xu… - Evolution …, 2024 - academic.oup.com
While temperature has been shown to affect the survival and growth of bacteria and their
phage parasites, it is unclear if trade-offs between phage resistance and other bacterial traits …

The rich tapestry of bacterial protein translocation systems

PJ Christie - The protein journal, 2019 - Springer
The translocation of proteins across membranes is a fundamental cellular function. Bacteria
have evolved a striking array of pathways for delivering proteins into or across cytoplasmic …

In vivo structure of the Legionella type II secretion system by electron cryotomography

D Ghosal, KW Kim, H Zheng, M Kaplan… - Nature …, 2019 - nature.com
The type II secretion system (T2SS) is a multiprotein envelope-spanning assembly that
translocates a wide range of virulence factors, enzymes and effectors through the outer …