The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …

Metallodrugs have a central role in the treatment and diagnosis of diseases. To overcome
potential toxicity and equip metal-based anticancer agents with biological activity, the choice …

A series of binuclear ruthenium (II) arene benzil bis (benzoylhydrazone) complexes (1–6) of
the common composition [(η6-arene) 2Ru2 (L) Cl2](arene= benzene or p-cymene; L= benzil …

With the discovery of cisplatin, a vast area of applications of metallodrugs in cancer
treatment was opened but due to the side effects caused by the cisplatin complexes …

This review focuses on organometallic nucleosides. It discusses: a) the synthetic methods
that enable the site-specific incorporation of organometallic entities into the nucleoside …

The development of multinuclear homometallic biologically active complexes is attractive for
modern bioinorganic chemistry, because this concept offers a multiplication of the …

The encapsulation of anticancer metal-based drugs within a protein nanocage represents a
valuable strategy to improve the efficacy and selectivity of these compounds towards cancer …

In recent years, the field of metal-based drugs has been dominated by other existing
precious metal drugs, and many researchers have focused their attention on the synthesis of …

Carbosilane metallodendrimers, based on the arene Ru (II) complex (CRD13) and
integrated to imino-pyridine surface groups have been investigated as an anticancer agent …

Thanks to development of erlotinib and other target therapy drugs the lung cancer treatment
have improved a lot in recent years. However, erlotinib-resistant lung cancer remains an …