Food choice as a key management strategy for functional gastrointestinal symptoms
PR Gibson, SJ Shepherd - Official journal of the American College …, 2012 - journals.lww.com
Recognition of food components that induce functional gut symptoms in patient's functional
bowel disorders (FBD) has been challenging. Food directly or indirectly provides …
bowel disorders (FBD) has been challenging. Food directly or indirectly provides …
[HTML][HTML] Stress-induced chronic visceral pain of gastrointestinal origin
B Greenwood-Van Meerveld… - Frontiers in Systems …, 2017 - frontiersin.org
Visceral pain is generally poorly localized and characterized by hypersensitivity to a
stimulus such as organ distension. In concert with chronic visceral pain, there is a high …
stimulus such as organ distension. In concert with chronic visceral pain, there is a high …
Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes
Astrocyte reactivity is disease‐and stimulus‐dependent, adopting either a proinflammatory
A1 phenotype or a protective, anti‐inflammatory A2 phenotype. Recently, we demonstrated …
A1 phenotype or a protective, anti‐inflammatory A2 phenotype. Recently, we demonstrated …
Tracing the dynamics of gene transcripts after organismal death
AE Pozhitkov, R Neme, T Domazet-Lošo… - Open …, 2017 - royalsocietypublishing.org
In life, genetic and epigenetic networks precisely coordinate the expression of genes—but in
death, it is not known if gene expression diminishes gradually or abruptly stops or if specific …
death, it is not known if gene expression diminishes gradually or abruptly stops or if specific …
[HTML][HTML] Identifying neutrophil-associated subtypes in ulcerative colitis and confirming neutrophils promote colitis-associated colorectal cancer
C Zhang, J Zhang, Y Zhang, Z Song, J Bian… - Frontiers in …, 2023 - frontiersin.org
Background Ulcerative colitis (UC) is a chronic inflammatory disease of the intestinal
mucosa, the incidence of which has increased worldwide. There is still a lack of clear …
mucosa, the incidence of which has increased worldwide. There is still a lack of clear …
Therapeutic Potential of Targeting Prokineticin Receptors in Diseases
M Vincenzi, A Kremić, A Jouve, R Lattanzi… - Pharmacological …, 2023 - ASPET
The prokineticins (PKs) were discovered approximately 20 years ago as small peptides
inducing gut contractility. Today, they are established as angiogenic, anorectic, and …
inducing gut contractility. Today, they are established as angiogenic, anorectic, and …
[HTML][HTML] Versatile role of prokineticins and prokineticin receptors in neuroinflammation
R Lattanzi, R Miele - Biomedicines, 2021 - mdpi.com
Prokineticins are a new class of chemokine-like peptides involved in a wide range of
biological and pathological activities. In particular, prokineticin 2 (PK2), prokineticin receptor …
biological and pathological activities. In particular, prokineticin 2 (PK2), prokineticin receptor …
Animal models of gastrointestinal and liver diseases. Animal models of visceral pain: pathophysiology, translational relevance, and challenges
B Greenwood-Van Meerveld… - American Journal …, 2015 - journals.physiology.org
Visceral pain describes pain emanating from the thoracic, pelvic, or abdominal organs. In
contrast to somatic pain, visceral pain is generally vague, poorly localized, and …
contrast to somatic pain, visceral pain is generally vague, poorly localized, and …
[HTML][HTML] Integrated multiple microarray studies by robust rank aggregation to identify immune-associated biomarkers in Crohn's disease based on three machine …
ZA Chen, H Ma, Y Wang, H Tian, J Mi, DM Yao… - Scientific Reports, 2023 - nature.com
Crohn's disease (CD) is a complex autoimmune disorder presumed to be driven by complex
interactions of genetic, immune, microbial and even environmental factors. Intrinsic …
interactions of genetic, immune, microbial and even environmental factors. Intrinsic …
Systematic analysis and characterization of long non-coding RNA genes in inflammatory bowel disease
The cases of inflammatory bowel disease (IBD) are increasing rapidly around the world. Due
to the multifactorial causes of IBD, there is an urgent need to understand the pathogenesis of …
to the multifactorial causes of IBD, there is an urgent need to understand the pathogenesis of …