Reconstruction of biochemical networks in microorganisms

AM Feist, MJ Herrgård, I Thiele, JL Reed… - Nature Reviews …, 2009 - nature.com
Abstract Systems analysis of metabolic and growth functions in microbial organisms is
rapidly developing and maturing. Such studies are enabled by reconstruction, at the …

Transition metal homeostasis: from yeast to human disease

MR Bleackley, RTA MacGillivray - Biometals, 2011 - Springer
Transition metal ions are essential nutrients to all forms of life. Iron, copper, zinc,
manganese, cobalt and nickel all have unique chemical and physical properties that make …

CORUM: the comprehensive resource of mammalian protein complexes—2019

M Giurgiu, J Reinhard, B Brauner… - Nucleic acids …, 2019 - academic.oup.com
CORUM is a database that provides a manually curated repository of experimentally
characterized protein complexes from mammalian organisms, mainly human (67%), mouse …

[HTML][HTML] The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information

T Chen, WH Yu, J Izard, OV Baranova… - Database, 2010 - academic.oup.com
The human oral microbiome is the most studied human microflora, but 53% of the species
have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are …

HiSCF: leveraging higher-order structures for clustering analysis in biological networks

L Hu, J Zhang, X Pan, H Yan, ZH You - Bioinformatics, 2021 - academic.oup.com
Motivation Clustering analysis in a biological network is to group biological entities into
functional modules, thus providing valuable insight into the understanding of complex …

CORUM: the comprehensive resource of mammalian protein complexes—2009

A Ruepp, B Waegele, M Lechner… - Nucleic acids …, 2010 - academic.oup.com
ABSTRACT CORUM is a database that provides a manually curated repository of
experimentally characterized protein complexes from mammalian organisms, mainly human …

Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of the Mutualistic Root Symbiont Piriformospora indica

A Zuccaro, U Lahrmann, U Güldener, G Langen… - PLoS …, 2011 - journals.plos.org
Recent sequencing projects have provided deep insight into fungal lifestyle-associated
genomic adaptations. Here we report on the 25 Mb genome of the mutualistic root symbiont …

CFinder: locating cliques and overlapping modules in biological networks

B Adamcsek, G Palla, IJ Farkas, I Derényi… - …, 2006 - academic.oup.com
Most cellular tasks are performed not by individual proteins, but by groups of functionally
associated proteins, often referred to as modules. In a protein assocation network modules …

Why do hubs tend to be essential in protein networks?

X He, J Zhang - PLoS genetics, 2006 - journals.plos.org
The protein–protein interaction (PPI) network has a small number of highly connected
protein nodes (known as hubs) and many poorly connected nodes. Genome-wide studies …

Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2′-O-methylation by nsp16/nsp10 protein complex

Y Chen, C Su, M Ke, X Jin, L Xu, Z Zhang, A Wu… - PLoS …, 2011 - journals.plos.org
The 5′-cap structure is a distinct feature of eukaryotic mRNAs, and eukaryotic viruses
generally modify the 5′-end of viral RNAs to mimic cellular mRNA structure, which is …