[HTML][HTML] Pharmacological mechanism of natural drugs and their active ingredients in the treatment of arrhythmia via calcium channel regulation

X Zhang, Y Gao, Y Zhou, Z Liu, R Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Arrhythmia is characterized by abnormal heartbeat rhythms and frequencies caused by
heart pacing and conduction dysfunction. Arrhythmia is the leading cause of death in …

Immunomodulatory effect of phytoactive compounds on human health: a narrative review integrated with bioinformatics approach

S Choudhary, S Khan, S Rustagi… - Current Topics in …, 2024 - ingentaconnect.com
Background: Immunomodulation is the modification of immune responses to control disease
progression. While the synthetic immunomodulators have proven efficacy, they are coupled …

A reverse docking approach to explore the anticancer potency of natural compounds by interfering metastasis and angiogenesis

AA Prome, TB Robin, N Ahmed, NA Rani… - Journal of …, 2023 - Taylor & Francis
Angiogenesis, which results in the formation of new blood and lymph vessels, is required to
serve metastatic cancer progression. Cancer medications may target these two …

Administration of protopine prevents mitophagy and acute lung injury in sepsis

Z Xiao, J Long, J Zhang, Z Qiu, C Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction: Sepsis is a severe life-threatening infection that induces a series of
dysregulated physiologic responses and results in organ dysfunction. Acute lung injury …

Protopine alleviates lipopolysaccharide-triggered intestinal epithelial cell injury through retarding the NLRP3 and NF-κB signaling pathways to reduce inflammation …

J Li, Z Xu, C OuYang, X Wu, Y Xie, J Xie - Allergologia et …, 2022 - all-imm.com
Background: Inflammatory bowel disease (IBD) is a common chronic intestinal disease.
Protopine isolated from different plants has been investigated to understand its special …

[HTML][HTML] Alkaloids in commercial preparations of California poppy–Quantification, intestinal permeability and microbiota interactions

A Chauveau, A Geirnaert, A Babst, A Treyer… - Biomedicine & …, 2023 - Elsevier
California poppy products are commonly used for the treatment of nervousness, anxiety and
sleeping disorders. Pharmacologically relevant constituents include the main alkaloids …

Computational Evaluation of N-Based Transannular Interactions in Some Model Fused Medium-Sized Heterocyclic Systems and Implications for Drug Design

R Griffith, JB Bremner - Molecules, 2023 - mdpi.com
As part of a project on fused medium-sized ring systems as potential drugs, we have
previously demonstrated the usefulness of Density Functional Theory (DFT) to evaluate …

Effects of dietary Bopu powder supplementation on serum antioxidant capacity, egg quality, and intestinal microbiota of laying hens

H Liu, Q Lin, X Liu, P Huang, Z Yang, M Cao… - Frontiers in …, 2022 - frontiersin.org
The purpose of this study was to investigate the effects of dietary Bopu powder
supplementation on the serum antioxidant capacity, serum biochemical indices, egg quality …

Exploring Chemical Composition, Antioxidant, Enzyme Inhibitory and Cytotoxic Properties of Glaucium acutidentatum Hausskn. & Bornm. from Turkey Flora: A Novel …

S Yagi, G Zengin, AI Uba, M Maciejewska-Turska… - Antioxidants, 2024 - mdpi.com
The present study was performed to determine the chemical constituents, cytotoxicity,
antioxidant and enzyme inhibition activities of the aerial parts of Glaucium acutidentatum …

Phytochemistry and pharmacology of alkaloids from Papaver spp.: a structure–activity based study

S Aalinezhad, F Dabaghian, A Namdari… - Phytochemistry …, 2024 - Springer
The genus Papaver L. includes 159 annual, biennial, and perennial species divided into 11
sections. Several studies on a few species in this genus have revealed that they have …