Signaling pathways in obesity: mechanisms and therapeutic interventions
X Wen, B Zhang, B Wu, H Xiao, Z Li, R Li… - Signal transduction and …, 2022 - nature.com
Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …
excessive fat accumulation in the body, obesity sharply increases the risk of several …
Circulating endocannabinoids: from whence do they come and where are they going?
CJ Hillard - Neuropsychopharmacology, 2018 - nature.com
The goal of this review is to summarize studies in which concentrations of circulating
endocannabinoids in humans have been examined in relationship to physiological …
endocannabinoids in humans have been examined in relationship to physiological …
Does stress influence sleep patterns, food intake, weight gain, abdominal obesity and weight loss interventions and vice versa?
Decades of research have reported only weak associations between the intakes of specific
foods or drinks and weight gain and obesity. Randomized controlled dietary intervention …
foods or drinks and weight gain and obesity. Randomized controlled dietary intervention …
Obesity and addiction: neurobiological overlaps
Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …
disorders in which the saliency of a specific type of reward (food or drug) becomes …
Reward, dopamine and the control of food intake: implications for obesity
The ability to resist the urge to eat requires the proper functioning of neuronal circuits
involved in top-down control to oppose the conditioned responses that predict reward from …
involved in top-down control to oppose the conditioned responses that predict reward from …
Obesity and leptin resistance: distinguishing cause from effect
Because leptin reduces food intake and body weight, the coexistence of elevated leptin
levels with obesity is widely interpreted as evidence of 'leptin resistance.'Indeed, obesity …
levels with obesity is widely interpreted as evidence of 'leptin resistance.'Indeed, obesity …
Is there a “metabolic-mood syndrome”? A review of the relationship between obesity and mood disorders
RB Mansur, E Brietzke, RS McIntyre - Neuroscience & Biobehavioral …, 2015 - Elsevier
Obesity and mood disorders are highly prevalent and co-morbid. Epidemiological studies
have highlighted the public health relevance of this association, insofar as both conditions …
have highlighted the public health relevance of this association, insofar as both conditions …
Stress, eating and the reward system
TC Adam, ES Epel - Physiology & behavior, 2007 - Elsevier
An increasing number of people report concerns about the amount of stress in their life. At
the same time obesity is an escalating health problem worldwide. Evidence is accumulating …
the same time obesity is an escalating health problem worldwide. Evidence is accumulating …
The tempted brain eats: pleasure and desire circuits in obesity and eating disorders
What we eat, when and how much, all are influenced by brain reward mechanisms that
generate “liking” and “wanting” for foods. As a corollary, dysfunction in reward circuits might …
generate “liking” and “wanting” for foods. As a corollary, dysfunction in reward circuits might …
Food and drug reward: overlapping circuits in human obesity and addiction
Both drug addiction and obesity can be defined as disorders in which the saliency value of
one type of reward (drugs and food, respectively) becomes abnormally enhanced relative to …
one type of reward (drugs and food, respectively) becomes abnormally enhanced relative to …