Cytokines are important mediators of various aspects of health and disease, including
appetite, glucose and lipid metabolism, insulin sensitivity, skeletal muscle hypertrophy and …

Adult skeletal muscle can regenerate in response to muscle damage. This ability is
conferred by the presence of myogenic stem cells called satellite cells. In response to stimuli …

The role of IL-6R/IL-6 axis in metabolic inflammation remains controversial. We determined
the changes in adipose tissue expression of IL-6R and IL-6 in obese, overweight, and lean …

Cachexia, the metabolic dysregulation leading to sustained loss of muscle and adipose
tissue, is a devastating complication of cancer and other chronic diseases. Interleukin-6 and …

IL-6 has emerged as an important cytokine upregulated in states of insulin resistance such
as type 2 diabetes. We evaluated the chronic effect of IL-6 on insulin signaling in 3T3-F442A …

The role of cytokines in cancer cachexia : Current Opinion in Supportive and Palliative Care The
role of cytokines in cancer cachexia : Current Opinion in Supportive and Palliative Care Log in …

A large number of observations point towards cytokines, polypeptides released mainly by
immune cells, as the molecules responsible for the metabolic derangements associated with …

Background Although the satellite cell (SC) is a key regulator of muscle growth during
development and muscle adaptation following exercise, the regulation of human muscle SC …

Although the search for the cachectic factor (s) started a long time ago, and although many
scientific and economic efforts have been devoted to its discovery, we are still a long way …

Skeletal muscle macrophages participate in repair and regeneration following injury.
However, their role in physiological adaptations to exercise is unexplored. We determined …