Metal-catalysed C–Het (F, O, S, N) and C–C bond arylation
B Zhao, T Rogge, L Ackermann, Z Shi - Chemical Society Reviews, 2021 - pubs.rsc.org
The formation of C–aryl bonds has been the focus of intensive research over the last
decades for the construction of complex molecules from simple, readily available feedstocks …
decades for the construction of complex molecules from simple, readily available feedstocks …
Late‐stage peptide diversification by position‐selective C− H activation
The late‐stage modification of structurally complex peptides bears great potential for drug
discovery, crop protection, and the pharmaceutical industry, among others. Whereas …
discovery, crop protection, and the pharmaceutical industry, among others. Whereas …
Sustainable protocols for direct C–H bond arylation of (hetero) arenes
G Albano, A Punzi, MAM Capozzi, GM Farinola - Green Chemistry, 2022 - pubs.rsc.org
Direct C–H bond arylation of (hetero) arenes is a very convenient approach for the synthesis
of a wide variety of molecular targets, including compounds of pharmaceutical interest and π …
of a wide variety of molecular targets, including compounds of pharmaceutical interest and π …
Ruthenium (II)-catalyzed C–H bond activation and functionalization
PB Arockiam, C Bruneau, PH Dixneuf - Chemical reviews, 2012 - ACS Publications
The catalytic functionalization of unreactive C− H bonds has recently brought a revolution in
synthetic methodologies for the production of pharmaceuticals and natural products and for …
synthetic methodologies for the production of pharmaceuticals and natural products and for …
Carboxylate-assisted ruthenium-catalyzed alkyne annulations by C–H/Het–H bond functionalizations
L Ackermann - Accounts of Chemical Research, 2014 - ACS Publications
To improve the atom-and step-economy of organic syntheses, researchers would like to
capitalize upon the chemistry of otherwise inert carbon–hydrogen (C–H) bonds. During the …
capitalize upon the chemistry of otherwise inert carbon–hydrogen (C–H) bonds. During the …
Weakly Coordinating Directing Groups for Ruthenium (II)‐Catalyzed C H Activation
S De Sarkar, W Liu, SI Kozhushkov… - … Synthesis & Catalysis, 2014 - Wiley Online Library
Synthetically useful functional groups, including ketones, amides, carbamates, carboxylic
acids, aldehydes or ethers, have been identified as weakly coordinating directing groups in …
acids, aldehydes or ethers, have been identified as weakly coordinating directing groups in …
Recent developments in ruthenium-catalyzed C–H arylation: Array of mechanistic manifolds
Functionalized biaryl-containing motifs are among the most valuable synthetic scaffolds in
organic chemistry with wide ranging commercial applications in pharmaceuticals, functional …
organic chemistry with wide ranging commercial applications in pharmaceuticals, functional …
sp 2 C–H bond activation in water and catalytic cross-coupling reactions
B Li, PH Dixneuf - Chemical Society Reviews, 2013 - pubs.rsc.org
The metal-catalysed successive activation and functionalisation of sp2 C–H bonds is the at
heart of synthetic innovations for the development of C–C bond cross-coupling processes …
heart of synthetic innovations for the development of C–C bond cross-coupling processes …
Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C–H bond functionalization
SI Kozhushkov, L Ackermann - Chemical science, 2013 - pubs.rsc.org
Significant progress has been accomplished in direct olefinations through twofold C–H bond
functionalization of arenes and heteroarenes employing readily accessible, selective and …
functionalization of arenes and heteroarenes employing readily accessible, selective and …
meta-Selective C–H bond alkylation with secondary alkyl halides
N Hofmann, L Ackermann - Journal of the American Chemical …, 2013 - ACS Publications
Ruthenium catalysts enabled C–H bond functionalizations on arenes with challenging
secondary alkyl halides. Particularly, ruthenium (II) biscarboxylate complexes proved to be …
secondary alkyl halides. Particularly, ruthenium (II) biscarboxylate complexes proved to be …