Tumor-targeting peptides from combinatorial libraries
Cancer is one of the major and leading causes of death worldwide. Two of the greatest
challenges in fighting cancer are early detection and effective treatments with no or …
challenges in fighting cancer are early detection and effective treatments with no or …
Combinatorial peptide libraries: mining for cell-binding peptides
BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …
a unique cellular landscape specific to the type and state of the cell. Ligands that …
Well-defined, reversible disulfide cross-linked micelles for on-demand paclitaxel delivery
To minimize premature release of drugs from their carriers during circulation in the blood
stream, we have recently developed reversible disulfide cross-linked micelles (DCMs) that …
stream, we have recently developed reversible disulfide cross-linked micelles (DCMs) that …
Peptides and peptide hormones for molecular imaging and disease diagnosis
Molecular imaging techniques are now indispensable tools in modern diagnostics, because
they are highly specific and can provide biological information at the molecular level in living …
they are highly specific and can provide biological information at the molecular level in living …
Nanoparticles in relation to peptide and protein aggregation
Over the past two decades, there has been considerable research interest in the use of
nanoparticles in the study of protein and peptide aggregation, and of amyloid-related …
nanoparticles in the study of protein and peptide aggregation, and of amyloid-related …
MAIA, Fc receptor–like 3, supersedes JUNO as IZUMO1 receptor during human fertilization
J Vondrakova, M Frolikova, L Ded, J Cerny… - Science …, 2022 - science.org
Gamete fusion is a critical event of mammalian fertilization. A random one-bead one-
compound combinatorial peptide library represented synthetic human egg mimics and …
compound combinatorial peptide library represented synthetic human egg mimics and …
Peptidic tumor targeting agents: the road from phage display peptide selections to clinical applications
KC Brown - Current pharmaceutical design, 2010 - ingentaconnect.com
Cancer has become the number one cause of death amongst Americans, killing
approximately 1,600 people per day. Novel methods for early detection and the …
approximately 1,600 people per day. Novel methods for early detection and the …
[HTML][HTML] Integrin targeting for tumor optical imaging
Y Ye, X Chen - Theranostics, 2011 - ncbi.nlm.nih.gov
Optical imaging has emerged as a powerful modality for studying molecular recognitions
and molecular imaging in a noninvasive, sensitive, and real-time way. Some advantages of …
and molecular imaging in a noninvasive, sensitive, and real-time way. Some advantages of …
Peptides for specific intracellular delivery and targeting of nanoparticles: implications for developing nanoparticle-mediated drug delivery
JB Delehanty, K Boeneman, CE Bradburne… - Therapeutic …, 2010 - Taylor & Francis
The use of peptides to mediate the delivery and uptake of nanoparticle (NP) materials by
mammalian cells has grown significantly over the past 10 years. This area of research has …
mammalian cells has grown significantly over the past 10 years. This area of research has …
Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels
YM Hyun, R Sumagin, PP Sarangi… - Journal of Experimental …, 2012 - rupress.org
The efficient trafficking of immune cells into peripheral nonlymphoid tissues is key to enact
their protective functions. Despite considerable advances in our understanding of cell …
their protective functions. Despite considerable advances in our understanding of cell …