Lesson from ecotoxicity: revisiting the microbial lipopeptides for the management of emerging diseases for crop protection
Microorganisms area treasure in terms of theproduction of various bioactive compounds
which are being explored in different arenas of applied sciences. In agriculture, microbes …
which are being explored in different arenas of applied sciences. In agriculture, microbes …
Computational approaches to the rational design of tubulin-targeting agents
H Pérez-Peña, AC Abel, M Shevelev, AE Prota… - Biomolecules, 2023 - mdpi.com
Microtubules are highly dynamic polymers of α, β-tubulin dimers which play an essential role
in numerous cellular processes such as cell proliferation and intracellular transport, making …
in numerous cellular processes such as cell proliferation and intracellular transport, making …
Molecular docking and dynamics simulation of protein β-tubulin and antifungal cyclic lipopeptides
To elucidate interactions between the antifungal cyclic lipopeptides iturin A, fengycin, and
surfactin produced by Bacillus bacteria and the microtubular protein β-tubulin in plant …
surfactin produced by Bacillus bacteria and the microtubular protein β-tubulin in plant …
Virtual screening of natural products database
JA de Sousa Luis, RPC Barros… - Mini Reviews in …, 2021 - ingentaconnect.com
Constant research on natural products has generated, over time, a large number of
compounds with the potential to be evaluated in several biological tests and subsequently …
compounds with the potential to be evaluated in several biological tests and subsequently …
[HTML][HTML] Application of ensemble pharmacophore-based virtual screening to the discovery of novel antimitotic tubulin inhibitors
Tubulin is a well-validated target for herbicides, fungicides, anti-parasitic, and anti-tumor
drugs. Many of the non-cancer tubulin drugs bind to its colchicine site but no colchicine-site …
drugs. Many of the non-cancer tubulin drugs bind to its colchicine site but no colchicine-site …
Comparative analysis of the interaction of mono-, dis-, and tris-azo food dyes with egg white lysozyme: A combined spectroscopic and computational simulation …
Egg white lysozyme plays an important role in the processing of high value-added poultry
products. Considering its applications in the food industry, lysozyme could interact with other …
products. Considering its applications in the food industry, lysozyme could interact with other …
Xanthatin and 8-epi-xanthatin as new potential colchicine binding site inhibitors: a computational study
D Alpízar-Pedraza, AN Veulens, YMÁ Ginarte… - Journal of Molecular …, 2023 - Springer
Context Phytocompounds xanthatin and 8-epi-xanthatin, obtained from Xanthium chinese
Mill, showed antitumoral activity in vitro related to the microtubules destabilizing properties …
Mill, showed antitumoral activity in vitro related to the microtubules destabilizing properties …
[HTML][HTML] Targeting the Cyclin-Dependent Kinase Family in Anticancer Drug Discovery: From Computational to Experimental Studies
Uncontrolled cell proliferation, primarily regulated by cyclin-dependent kinases (CDKs), is a
critical driver of cancer progression, with dysregulation of CDKs contributing to various …
critical driver of cancer progression, with dysregulation of CDKs contributing to various …
[PDF][PDF] Xantatina y 8-epi-xantatina como inhibidores de la quinesina Eg5. Un análisis computacional
EC Araújo - fototeca.uh.cu
El cáncer comprende un grupo de enfermedades con características similiares. Uno de los
rasgos más importantes de este tipo de dolencias es la desregulación de los procesos que …
rasgos más importantes de este tipo de dolencias es la desregulación de los procesos que …
[PDF][PDF] Xantanólidos (xantatina y 8-epi-xantatina) moléculas con actividad antimitótica: Modelación in silico de su posible mecanismo de interacción con la tubulina.
DA Pedraza, CYMÁ Ginarte - fototeca.uh.cu
Los isómeros xantatina y 8-epi-xanntatina, obtenidos de Xanthium strumarium, poseen
actividad antitumoral in vitro, la cual se ha relacionado con las propiedades …
actividad antitumoral in vitro, la cual se ha relacionado con las propiedades …