Long term structural and functional neural changes following a single infusion of Ketamine in PTSD

O Duek, N Korem, Y Li, B Kelmendi, S Amen… - …, 2023 - nature.com
NMDA receptor antagonists have a vital role in extinction, learning, and reconsolidation
processes. During the reconsolidation window, memories are activated into a labile state …

[HTML][HTML] Fear attenuation collaborations to optimize translation.

MH Monfils, HJ Lee, M Raskin, Y Niv… - Behavioral …, 2024 - psycnet.apa.org
Here, we describe the efforts we dedicated to the challenge of modifying entrenched
emotionally laden memories. In recent years, through a number of collaborations and using …

[PDF][PDF] Clinical translation of memory reconsolidation research: Therapeutic methodology for transformational change by erasing implicit emotional learnings driving …

B Ecker - 2017 - osf.io
After 20 years of laboratory study of memory reconsolidation, the translation of research
findings into clinical application has recently been the topic of a rapidly growing number of …

[HTML][HTML] Memory reconsolidation and the crisis of mechanism in psychotherapy

B Ecker, A Vaz - New Ideas in Psychology, 2022 - Elsevier
Internal mechanisms of lasting therapeutic change have eluded empirical identification
despite decades of outcome research. A breakthrough may be at hand in neurobiological …

Reminder duration determines threat memory modification in humans

J Hu, W Wang, P Homan, P Wang, X Zheng… - Scientific reports, 2018 - nature.com
Memory reminders can return a memory into an unstable state such that it will decay unless
actively restabilized into long-term memory through reconsolidation. Exposure to a memory …

Destabilizing different strengths of fear memories requires different degrees of prediction error during retrieval

W Chen, J Li, L Xu, S Zhao, M Fan… - Frontiers in behavioral …, 2021 - frontiersin.org
Reactivation of consolidated memories can induce a labile period, in which these
reactivated memories might be susceptible to change and need reconsolidation. Prediction …

Limited replicability of drug-induced amnesia after contextual fear memory retrieval in rats

N Schroyens, JM Alfei, AE Schnell, L Luyten… - … of Learning and …, 2019 - Elsevier
With the ultimate goal of investigating boundary conditions for post-reactivation amnesia, we
set out to replicate studies in which systemic, post-reactivation administration of midazolam …

Reconsolidation and fear extinction: An update

M Raskin, MH Monfils - Fear Extinction: From Basic Neuroscience to …, 2023 - Springer
Fear memories can be updated behaviorally by delivering extinction trials during the
reconsolidation window, which results in a persistent attenuation of fear memories (Monfils …

Reactivation-dependent amnesia for contextual fear memories: Evidence for publication bias

N Schroyens, EL Sigwald, W Van Den Noortgate… - Eneuro, 2021 - eneuro.org
Research on memory reconsolidation has been booming in the last two decades, with
numerous high-impact publications reporting promising amnestic interventions in rodents …

Dissociating retrieval-dependent contextual aversive memory processes in female rats: Are there cycle-dependent differences?

JM Franzen, M Giachero, LJ Bertoglio - Neuroscience, 2019 - Elsevier
Upon retrieval, aversive associative memories may engage alternative processes
depending on the conditioned stimulus exposure length. Generally, a short session …