[HTML][HTML] Synthetic approaches and pharmacological activity of 1, 3, 4-oxadiazoles: a review of the literature from 2000–2012

CS De Oliveira, BF Lira, JM Barbosa-Filho… - Molecules, 2012 - mdpi.com
Molecules | Free Full-Text | Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles:
A Review of the Literature from 2000–2012 Next Article in Journal Chemical Composition of …

Oxadiazole: A highly versatile scaffold in drug discovery

N Desai, J Monapara, A Jethawa… - Archiv der …, 2022 - Wiley Online Library
As a pharmacologically important heterocycle, oxadiazole paved the way to combat the
problem associated with the confluence of many commercially available drugs with different …

Therapeutic potential of quinazoline derivatives for Alzheimer's disease: A comprehensive review

Z Haghighijoo, L Zamani, F Moosavi… - European journal of …, 2022 - Elsevier
Quinazolines are considered as a promising class of bioactive heterocyclic compounds with
broad properties. Particularly, the quinazoline scaffold has an impressive role in the design …

Synthesis of 2-Amino-1,3,4-oxadiazoles and 2-Amino-1,3,4-thiadiazoles via Sequential Condensation and I2-Mediated Oxidative C–O/C–S Bond Formation

P Niu, J Kang, X Tian, L Song, H Liu, J Wu… - The Journal of …, 2015 - ACS Publications
2-Amino-substituted 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles were synthesized via
condensation of semicarbazide/thiosemicarbazide and the corresponding aldehydes …

Current perspectives on quinazolines with potent biological activities: A review

T Gupta, A Rohilla, A Pathak, MJ Akhtar… - Synthetic …, 2018 - Taylor & Francis
Quinazoline is a heterocyclic compound having biological activities. It is aromatic in nature
having bicyclic structure containing benzene ring and pyrimidine ring. Quinazoline and its …

4-(3H)-quinazolinones N-3 substituted with a five membered heterocycle: A promising scaffold towards bioactive molecules

F Plescia, B Maggio, G Daidone, D Raffa - European Journal of Medicinal …, 2021 - Elsevier
The quinazolinone nucleus represents, among the class of fused heterocycles, a very
important scaffold to obtain molecules with biological activities. A review of literature …

Synthesis and biological activities of oxadiazole derivatives: a review

A Vaidya, S Jain, P Jain, P Jain, N Tiwari… - Mini Reviews in …, 2016 - ingentaconnect.com
Recently, there has been wide interest in compounds containing the oxadiazole scaffold
because of their unique chemical structure and their broad spectrum of biological properties …

Synthesis of a series of novel 2-amino-5-substituted 1, 3, 4-oxadiazole and 1, 3, 4-thiadiazole derivatives as potential anticancer, antifungal and antibacterial agents

EC Pham, TN Truong, NH Dong, DD Vo… - Medicinal …, 2022 - ingentaconnect.com
Background: Many compounds containing a five-membered heterocyclic ring display
exceptional chemical properties and versatile biological activities. Objective: The objective …

[HTML][HTML] Molecular docking and anticonvulsant activity of newly synthesized quinazoline derivatives

HA Abuelizz, R El Dib, M Marzouk, EH Anouar… - Molecules, 2017 - mdpi.com
A new series of quinazoline-4 (3 H)-ones are evaluated for anticonvulsant activity. After
intraperitoneal (ip) injection to albino mice at a dose of 100 mg/kg body weight, synthesized …

Highly selective and sensitive pH-responsive fluorescent probe in living Hela and HUVEC cells

HS Lv, J Liu, J Zhao, BX Zhao, JY Miao - Sensors and Actuators B …, 2013 - Elsevier
A new fluorescent probe has been synthesized, characterized and evaluated in living cells
as an intracellular pH indicator. The probe is designed based on the fluorescence switching …