Increased interleukin-6 levels associated with malaria infection and disease severity: a systematic review and meta-analysis
Abstract Interleukin-6 (IL-6) is generated by immune cells during infection with malaria
parasites and they are associated with the immunopathogenesis of malaria. The present …
parasites and they are associated with the immunopathogenesis of malaria. The present …
T cell-derived IL-10 and its impact on the regulation of host responses during malaria
APF do Rosario, J Langhorne - International journal for parasitology, 2012 - Elsevier
Despite intense research, malaria still is the one of the most devastating diseases killing
more people than any other parasitic infection. In an attempt to control the infection, the host …
more people than any other parasitic infection. In an attempt to control the infection, the host …
Cytokine profiles in Malawian children presenting with uncomplicated malaria, severe malarial anemia, and cerebral malaria
WL Mandala, CL Msefula, EN Gondwe… - Clinical and vaccine …, 2017 - Am Soc Microbiol
Proinflammatory cytokines are involved in clearance of Plasmodium falciparum, and very
high levels of these cytokines have been implicated in the pathogenesis of severe malaria …
high levels of these cytokines have been implicated in the pathogenesis of severe malaria …
Asymptomatic malaria infection is maintained by a balanced pro-and anti-inflammatory response
A Frimpong, J Amponsah, AS Adjokatseh… - Frontiers in …, 2020 - frontiersin.org
Background Pro-and anti-inflammatory cytokines are important mediators of immunity and
are associated with malaria disease outcomes. However, their role in the establishment of …
are associated with malaria disease outcomes. However, their role in the establishment of …
Proinflammatory and regulatory cytokines and chemokines in infants with uncomplicated and severe Plasmodium falciparum malaria
E Ayimba, J Hegewald, AY Segbena… - Clinical & …, 2011 - academic.oup.com
Cytokine and chemokine levels were studied in infants (< 5 years) with uncomplicated (MM)
and severe malaria tropica (SM), and in Plasmodium falciparum infection-free controls …
and severe malaria tropica (SM), and in Plasmodium falciparum infection-free controls …
Increased interferon-γ levels and risk of severe malaria: a meta-analysis
A Mahittikorn, W Mala, FR Masangkay, KU Kotepui… - Scientific reports, 2022 - nature.com
Interferon (IFN)-γ contributes to the pathogenesis of severe malaria; however, its mechanism
remains unclear. Herein, differences in IFN-γ levels between patients with severe and …
remains unclear. Herein, differences in IFN-γ levels between patients with severe and …
γδ T cells and CD14+ Monocytes Are Predominant Cellular Sources of Cytokines and Chemokines Associated With Severe Malaria
DI Stanisic, J Cutts, E Eriksson… - The Journal of …, 2014 - academic.oup.com
Background. Severe malaria (SM) is associated with high levels of cytokines such as tumor
necrosis factor (TNF), interleukin 1 (IL-1), and interleukin 6 (IL-6). The role of chemokines is …
necrosis factor (TNF), interleukin 1 (IL-1), and interleukin 6 (IL-6). The role of chemokines is …
Networking the host immune response in Plasmodium vivax malaria
Background Plasmodium vivax malaria clinical outcomes are a consequence of the
interaction of multiple parasite, environmental and host factors. The host molecular and …
interaction of multiple parasite, environmental and host factors. The host molecular and …
Circulating IL-6, IL-10, and TNF-alpha and IL-10/IL-6 and IL-10/TNF-alpha ratio profiles of polyparasitized individuals in rural and urban areas of gabon
NP M'bondoukwé, R Moutongo… - PLoS neglected …, 2022 - journals.plos.org
Malaria, blood-borne filarial worms and intestinal parasites are all endemic in Gabon. This
geographical co-distribution leads to polyparasitism and, consequently, the possibility of …
geographical co-distribution leads to polyparasitism and, consequently, the possibility of …
Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea
L Schofield, LJ Ioannidis, S Karl, LJ Robinson, QY Tan… - BMC medicine, 2017 - Springer
Background γδ T cells are important for both protective immunity and immunopathogenesis
during malaria infection. However, the immunological processes determining beneficial or …
during malaria infection. However, the immunological processes determining beneficial or …