Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

Sepsis is a persistent systemic inflammatory condition involving multiple organ failures
resulting from a dysregulated immune response to infection, and one of the hallmarks of …

The tumour-associated microbiota is an intrinsic component of the tumour microenvironment
across human cancer types,. Intratumoral host–microbiota studies have so far largely relied …

Myeloid cells are a significant proportion of leukocytes within tissues, comprising
granulocytes, monocytes, dendritic cells, and macrophages. With the identification of various …

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal
tract that results from dysfunction in innate and/or adaptive immune responses. Impaired …

Immune cell locomotion is associated with amoeboid migration, a flexible mode of
movement, which depends on rapid cycles of actin polymerization and actomyosin …

Inflammation is a highly dynamic process with immune cells that continuously interact with
each other and parenchymal components as they migrate through tissue. The dynamic …

Neutrophil granulocytes, or neutrophils, are the most abundant circulating leukocytes in
humans and indispensable for antimicrobial immunity, as exemplified in patients with inborn …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are associated with
high morbidity and mortality. Excessive neutrophil infiltration into the pulmonary airspace is …

Macrophages are key immune cells with important roles for tissue surveillance in almost all
mammalian organs. Cellular networks made up of many individual macrophages allow for …