Diagnosis and management of acute ischaemic stroke

R Hurford, A Sekhar, TAT Hughes, KW Muir - Practical Neurology, 2020 - pn.bmj.com
Acute ischaemic stroke is a major public health priority and will become increasingly
relevant to neurologists of the future. The cornerstone of effective stroke care continues to be …

Overview of acute ischemic stroke evaluation and management

TF Hasan, H Hasan, RE Kelley - Biomedicines, 2021 - mdpi.com
Stroke is a major contributor to death and disability worldwide. Prior to modern therapy, post-
stroke mortality was approximately 10% in the acute period, with nearly one-half of the …

Impaired breakdown of bradykinin and its metabolites as a possible cause for pulmonary edema in COVID-19 infection

S de Maat, Q de Mast, AHJ Danser… - … in thrombosis and …, 2020 - thieme-connect.com
A growing body of clinical evidence shows that vascular leakage leads to pulmonary edema
in coronavirus disease 2019 (COVID-19) patients. Coronaviruses including severe acute …

Bradykinin: inflammatory product of the coagulation system

Z Hofman, S de Maat, CE Hack, C Maas - Clinical reviews in allergy & …, 2016 - Springer
Episodic and recurrent local cutaneous or mucosal swelling are key features of
angioedema. The vasoactive agents histamine and bradykinin are highly implicated as …

The Chinese Stroke Association scientific statement: intravenous thrombolysis in acute ischaemic stroke

Q Dong, Y Dong, L Liu, A Xu, Y Zhang… - Stroke and Vascular …, 2017 - svn.bmj.com
The most effective medical treatment for acute ischaemic stroke (AIS) is to offer intravenous
thrombolysis during the ultra-early period of time after the onset. Even based on the …

[HTML][HTML] Hereditary angioedema: the plasma contact system out of control

S De Maat, ZLM Hofman, C Maas - Journal of Thrombosis and Haemostasis, 2018 - Elsevier
The plasma contact system contributes to thrombosis in experimental models. Even though
our standard blood coagulation tests are prolonged when plasma lacks contact factors, this …

[HTML][HTML] Thrombolysis and thrombectomy for acute ischaemic stroke

S El Tawil, KW Muir - Clinical Medicine, 2017 - Elsevier
The likelihood of disability-free recovery after acute ischemic stroke is significantly improved
by reperfusion either by intravenous thrombolytic drug treatment or with endovascular …

Orolingual angioedema during or after thrombolysis for cerebral ischemia

F Myslimi, F Caparros, N Dequatre-Ponchelle, S Moulin… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Orolingual angioedema (OLAE) is a life-threatening
complication of intravenous thrombolysis. Our objective was to compare outcomes of …

Hereditary angioedema with normal C1 inhibitor: update on evaluation and treatment

M Magerl, AE Germenis, C Maas… - … and Allergy Clinics, 2017 - immunology.theclinics.com
Hereditary angioedema (HAE) was first described by Dinkelacker 1 and Quincke 2 in 1882
and a few years later by Osler 3 as recurrent angioedema with a positive family history. In …

Angiotensin-converting enzyme inhibitor and other drug-associated angioedema

C Stone, NJ Brown - Immunology and Allergy Clinics, 2017 - immunology.theclinics.com
Angioedema is characterized by localized deep dermal, subcutaneous, and/or mucosal
edema resulting from increased vasodilatation and vascular permeability. Nonsteroidal …