Advances in DBS technology and novel applications: Focus on movement disorders
Abstract Purpose of Review Deep brain stimulation (DBS) is an established treatment in
several movement disorders, including Parkinson's disease, dystonia, tremor, and Tourette …
several movement disorders, including Parkinson's disease, dystonia, tremor, and Tourette …
Gaps and roadmap of novel neuromodulation targets for treatment of gait in Parkinson's disease
Gait issues in Parkinson's disease (PD) are common and can be highly disabling. Although
levodopa and deep brain stimulation (DBS) of the subthalamic nucleus and the globus …
levodopa and deep brain stimulation (DBS) of the subthalamic nucleus and the globus …
Mapping of subthalamic nucleus using microelectrode recordings during deep brain stimulation
Alongside stereotactic magnetic resonance imaging, microelectrode recording (MER) is
frequently used during the deep brain stimulation (DBS) surgery for optimal target …
frequently used during the deep brain stimulation (DBS) surgery for optimal target …
Subthalamic and nigral neurons are differentially modulated during parkinsonian gait
A Gulberti, JR Wagner, MA Horn, JH Reuss, M Heise… - Brain, 2023 - academic.oup.com
The parkinsonian gait disorder and freezing of gait are therapeutically demanding symptoms
with considerable impact on quality of life. The aim of this study was to assess the role of …
with considerable impact on quality of life. The aim of this study was to assess the role of …
Electrical activation of the pedunculopontine tegmental nucleus modulates the neuronal activities of the subthalamic nucleus and the substantia nigra pars reticulata in …
The subthalamic nucleus (STN), substantia nigra pars reticulata (SNr), and
pedunculopontine tegmental nucleus (PPTg) are reciprocally connected brain regions that …
pedunculopontine tegmental nucleus (PPTg) are reciprocally connected brain regions that …
Electrophysiological Characterization of Substantia Nigra Pars Reticulata in Anesthetized Rats
X Liu, Q Zhang, Y Wang, F Chen - Journal of Shanghai Jiaotong University …, 2022 - Springer
The substantia nigra pars reticulate (SNr), which plays a pivotal role in motor control, is the
key structure in integrating information for cortex, basal ganglia and thalamus. Abnormal gait …
key structure in integrating information for cortex, basal ganglia and thalamus. Abnormal gait …
Mid-Range Frequency Amplification of Neural Signals to Improve Spike Detection
EL Ashbolt - 2021 - search.proquest.com
Microelectrode recordings (MERs) are used for target confirmation during deep brain
stimulation (DBS) electrode placement surgery by listening for characteristic neural activity …
stimulation (DBS) electrode placement surgery by listening for characteristic neural activity …
Technique to improve deep brain stimulation targeting during intraoperative microelectrode recordings
G Mcconnell, H Li - US Patent 11,529,519, 2022 - Google Patents
(57) ABSTRACT A method of localizing brain regions for the purpose of guiding placement
of electrodes and related implants is disclosed. The inventive method involves effecting a …
of electrodes and related implants is disclosed. The inventive method involves effecting a …