Artificial intelligence-enabled quantitative phase imaging methods for life sciences

J Park, B Bai, DH Ryu, T Liu, C Lee, Y Luo, MJ Lee… - Nature …, 2023 - nature.com
Quantitative phase imaging, integrated with artificial intelligence, allows for the rapid and
label-free investigation of the physiology and pathology of biological systems. This review …

AI on a chip

A Isozaki, J Harmon, Y Zhou, S Li, Y Nakagawa… - Lab on a Chip, 2020 - pubs.rsc.org
Artificial intelligence (AI) has dramatically changed the landscape of science, industry,
defence, and medicine in the last several years. Supported by considerably enhanced …

High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy

J Demas, J Manley, F Tejera, K Barber, H Kim… - Nature …, 2021 - nature.com
Two-photon microscopy has enabled high-resolution imaging of neuroactivity at depth within
scattering brain tissue. However, its various realizations have not overcome the tradeoffs …

Time-stretch LiDAR as a spectrally scanned time-of-flight ranging camera

Y Jiang, S Karpf, B Jalali - Nature photonics, 2020 - nature.com
The need for imaging and ranging in robotics has brought LiDAR (light detection and
ranging) to the forefront of consumer technology. Among various approaches, time-of-flight …

Kilohertz two-photon fluorescence microscopy imaging of neural activity in vivo

J Wu, Y Liang, S Chen, CL Hsu, M Chavarha… - Nature …, 2020 - nature.com
Understanding information processing in the brain requires monitoring neuronal activity at
high spatiotemporal resolution. Using an ultrafast two-photon fluorescence microscope …

Single-shot ultrafast optical imaging

J Liang, LV Wang - Optica, 2018 - opg.optica.org
Single-shot ultrafast optical imaging can capture two-dimensional transient scenes in the
optical spectral range at≥ 100 million frames per second. This rapidly evolving field …

High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics

JL Fan, JA Rivera, W Sun, J Peterson… - Nature …, 2020 - nature.com
Understanding the structure and function of vasculature in the brain requires us to monitor
distributed hemodynamics at high spatial and temporal resolution in three-dimensional (3D) …

Ultrafast two-photon fluorescence imaging of cerebral blood circulation in the mouse brain in vivo

G Meng, J Zhong, Q Zhang, JSJ Wong… - Proceedings of the …, 2022 - National Acad Sciences
Characterizing blood flow dynamics in vivo is critical to understanding the function of the
vascular network under physiological and pathological conditions. Existing methods for …

Speed scaling in multiphoton fluorescence microscopy

J Wu, N Ji, KK Tsia - Nature Photonics, 2021 - nature.com
After over 30 years of advances, multiphoton microscopy (MPM) is now instrumental in a
wide range of in vivo biological imaging applications. However, it has, until recently …

High-throughput imaging flow cytometry by optofluidic time-stretch microscopy

C Lei, H Kobayashi, Y Wu, M Li, A Isozaki… - Nature protocols, 2018 - nature.com
The ability to rapidly assay morphological and intracellular molecular variations within large
heterogeneous populations of cells is essential for understanding and exploiting cellular …