Circular RNA in cardiovascular disease: Expression, mechanisms and clinical prospects

Y Tang, J Bao, J Hu, L Liu, DY Xu - Journal of cellular and …, 2021 - Wiley Online Library
Circular RNAs (circRNAs) are a group of covalently closed, endogenous, non‐coding RNAs,
which exist widely in human tissues including the heart. Increasing evidence has shown that …

Recent advances of using exosomes as diagnostic markers and targeting carriers for cardiovascular disease

N Li, T Zhang, L Zhu, L Sun, G Shao… - Molecular …, 2023 - ACS Publications
Cardiovascular diseases (CVDs) are the leading cause of human death worldwide.
Exosomes act as endogenous biological vectors; they possess advantages of low …

Peripheral blood circular RNA hsa_circ_0124644 can be used as a diagnostic biomarker of coronary artery disease

Z Zhao, X Li, C Gao, D Jian, P Hao, L Rao, M Li - Scientific reports, 2017 - nature.com
The aim of the present study was to investigate the expression of circular RNAs (circRNAs)
in the peripheral blood of coronary artery disease (CAD) patients and the potential use of …

Identification of circular RNA Hsa_circ_0001879 and Hsa_circ_0004104 as novel biomarkers for coronary artery disease

L Wang, C Shen, Y Wang, T Zou, H Zhu, X Lu, L Li… - Atherosclerosis, 2019 - Elsevier
Background and aims The role of circular RNAs (circRNAs) in coronary artery disease
(CAD) remains elusive. The aim of the present study was to profile circRNAs expression in …

Plasma‐derived exosomal circular RNA hsa_circ_0005540 as a novel diagnostic biomarker for coronary artery disease

W Wu, Y Pan, M Cai, J Cen, C Chen, L Zheng… - Disease …, 2020 - Wiley Online Library
Background. Exosomes exist in almost all body fluid and contain diverse biological contents
which may be reflective of disease state. Circular RNAs (circRNAs) are stable in structure …

[HTML][HTML] CircRNA ZNF609 in peripheral blood leukocytes acts as a protective factor and a potential biomarker for coronary artery disease

B Liang, M Li, Q Deng, C Wang, J Rong… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Circular RNAs (circRNAs) have been reported to aberrantly express in coronary
artery disease (CAD). Due to their special structures, circRNAs have the potential to be …

Plasma exosomal S1PR5 and CARNS1 as potential non-invasive screening biomarkers of coronary heart disease

F Xiong, R Mao, R Zhao, L Zhang, K Tan… - Frontiers in …, 2022 - frontiersin.org
Background Early diagnosis and treatment significantly improve the prognosis of coronary
heart disease (CHD), but no convenient screening tools are available. This study aims to …

The diagnostic accuracy of cardiac ultrasound for acute myocardial ischemia in the emergency department: a systematic review and meta-analysis

V Zarama, MC Arango-Granados… - Scandinavian Journal of …, 2024 - Springer
Background Chest pain is responsible for millions of visits to the emergency department
(ED) annually. Cardiac ultrasound can detect ischemic changes, but varying accuracy …

Deep Learning in Heart Sound Analysis: From Techniques to Clinical Applications

Q Zhao, S Geng, B Wang, Y Sun, W Nie, B Bai… - Health Data …, 2024 - spj.science.org
Importance: Heart sound auscultation is a routinely used physical examination in clinical
practice to identify potential cardiac abnormalities. However, accurate interpretation of heart …

Plasma-derived exosomal let-7c-5p, miR-335–3p, and miR-652–3p as potential diagnostic biomarkers for stable coronary artery disease

J Han, X Cui, T Yuan, Z Yang, Y Liu, Y Ren… - Frontiers in …, 2023 - frontiersin.org
Objectives: Circulating exosomal microRNAs (miRNAs) have been identified as promising
biomarkers for diagnosis of cardiovascular diseases. Nevertheless, the diagnostic potential …