Emerging biomarkers in the diagnosis of prostate cancer

X Filella, E Fernández-Galan… - Pharmacogenomics …, 2018 - Taylor & Francis
Prostate cancer (PCa) is the second most common cancer in men worldwide. A large
proportion of PCa are latent, never destined to progress or affect the patients' life. It is of …

Prostate cancer detection and prognosis: from prostate specific antigen (PSA) to exosomal biomarkers

X Filella, L Foj - International journal of molecular sciences, 2016 - mdpi.com
Prostate specific antigen (PSA) remains the most used biomarker in the management of
early prostate cancer (PCa), in spite of the problems related to false positive results and …

Prostate cancer screening in men aged 50–69 years (STHLM3): a prospective population-based diagnostic study

H Grönberg, J Adolfsson, M Aly, T Nordström… - The lancet …, 2015 - thelancet.com
Background The prostate-specific antigen (PSA) test is used to screen for prostate cancer
but has a high false-positive rate that translates into unnecessary prostate biopsies and …

Multicenter evaluation of the prostate health index to detect aggressive prostate cancer in biopsy naive men

C De La Calle, D Patil, JT Wei, DS Scherr… - The Journal of …, 2015 - auajournals.org
Purpose: We evaluated the ability of PHI to discriminate aggressive prostate cancer from
indolent or no cancer in a biopsy naïve population. Materials and Methods: Two …

Prostate health index and multiparametric MRI: partners in crime fighting overdiagnosis and overtreatment in prostate cancer

M Ferro, F Crocetto, D Bruzzese, M Imbriaco, F Fusco… - Cancers, 2021 - mdpi.com
Simple Summary In the last decades, the widespread use of PSA as the standard tool for
prostate cancer diagnosis led to a high rate of overdiagnosis and overtreatment. More …

The present and future of biomarkers in prostate cancer: proteomics, genomics, and immunology advancements: supplementary issue: biomarkers and their essential …

PO Gaudreau, J Stagg, D Soulières… - Biomarkers in …, 2016 - journals.sagepub.com
Prostate cancer (PC) is the second most common form of cancer in men worldwide.
Biomarkers have emerged as essential tools for treatment and assessment since the …

[HTML][HTML] Update–2022 Canadian urological association recommendations on prostate cancer screening and early diagnosis: endorsement of the 2021 cancer care …

RJ Mason, K Marzouk, A Finelli, F Saad… - Canadian Urological …, 2022 - ncbi.nlm.nih.gov
Prostate cancer remains the most commonly diagnosed noncutaneous malignancy among
Canadian men and is the third leading cause of cancer-related death. In 2016, an estimated …

[HTML][HTML] The clinical effectiveness and cost-effectiveness of the PROGENSA® prostate cancer antigen 3 assay and the Prostate Health Index in the diagnosis of …

A Nicholson, J Mahon, A Boland, S Beale… - Health Technology …, 2015 - europepmc.org
Background There is no single definitive test to identify prostate cancer in men. Biopsies are
commonly used to obtain samples of prostate tissue for histopathological examination …

Beyond PSA: the role of prostate health index (phi)

M Ferro, O De Cobelli, G Lucarelli, A Porreca… - International Journal of …, 2020 - mdpi.com
Background: Widespread use of prostate specific antigen (PSA) in screening procedures
allowed early identification of an increasing number of prostate cancers (PCas), mainly …

Testosterone replacement therapy and risk of favorable and aggressive prostate cancer

S Loeb, Y Folkvaljon, JE Damber, J Alukal… - Journal of Clinical …, 2017 - ascopubs.org
Purpose The association between exposure to testosterone replacement therapy (TRT) and
prostate cancer risk is controversial. The objective was to examine this association through …