High blood pressure (BP) remains the major heritable and modifiable risk factor for
cardiovascular disease. Persistent high BP, or hypertension, is a complex trait with both …

Abstract Background and Purpose Local blood flow regulation relies on the coordination
between neurons and pericyte‐containing capillaries. Pericyte relaxation and contraction …

Benzodiazepines (BDZs) and non-BDZ sedative-hypnotics are effective for the management
of chronic insomnia; however, they are associated with adverse effects such as headache …

Background Pulmonary arterial hypertension (PAH) in systemic sclerosis (SS) identifies a
poor prognosis subset of patients. Recent studies suggested a “metabolic theory” on the …

The clinical administration of GABAergic medications leads to hypotension which has
classically been attributed to the modulation of neuronal activity in the central and peripheral …

Background We aimed to investigate whether the facilitating effect of H 2 S on the
baroreceptor reflex is associated with the GABA A receptor, K ATP channel and L-type Ca …

Background: Hypertension is considered an independent risk factor for cardiovascular
mortality in diabetic patients. The present study was designed to determine the role of …

Background: Diabetes mellitus can change the risk of developing cancer. Cisplatin (CP) is a
common antineoplastic drug. The major side effect of CP is nephrotoxicity. Gamma amino …

The effects of glufimet and phenibut (glutamic acid and GABA derivatives, respectively) on
concentration of inducible NO synthase and cGMP in LPS-activated mouse peritoneal …

Betahistine and Piracetam are routine drugs in neurological practice, which are used to
correct cerebral circulation disorders. The clinical efficacy of these drugs can be caused not …