The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …

“Dietary fiber”(DF) refers to a type of carbohydrate that cannot be digested fully. DF is not an
essential nutrient, but it plays an important part in enhancing digestive capacity and …

Great progress has been made in understanding gut microbiomes' products and their effects
on health and disease. Less attention, however, has been given to the inputs that gut …

Post-translational modifications (PTMs) on histones are a key source of regulation on
chromatin through impacting cellular processes, including gene expression. These PTMs …

Dysregulation of histone modifications has been implicated in the pathogenesis of both
inflammatory bowel disease (IBD) and colorectal cancer (CRC). These diseases are …

Adult humans harbor at least as many microbial cells as eukaryotic ones. The largest
compartment of this diverse microbial population, the gut microbiota, encompasses the …

The regulatory pathways by which gut microbiota potentially shape host life histories remain
largely untested, however, a constellation of research suggests that gut bacteria likely have …

Background Whilst the incidence of neurological diseases is increasing worldwide,
treatment remains mostly limited to symptom management. The gut− brain axis, which …

Chromatin plays a central role in the conversion of energy in cells: alteration of chromatin
structure to make DNA accessible consumes energy, and compaction of chromatin …

Short-chain fatty acids (SCFAs), such as acetate, propionate, and butyrate, modulate
immune cell functions, particularly macrophages. This review explores the potential …