Introduction Vaccines based on multiple antigens often induce an immune response, which
is higher than that triggered by each single component, with antibodies acting cooperatively …

Abstract Background The Meningococcal Antigen Typing System (MATS) was developed to
identify meningococcus group B strains with a high likelihood of being covered by the …

Introduction Recombinant surface protein meningococcal serogroup B (MenB) vaccines are
available but with different antigen compositions, leading to differences between vaccines in …

Invasive meningococcal disease (IMD) is a major public health concern because of its high
case fatality, long-term morbidity, and potential to course with outbreaks. IMD caused by …

The ability of Neisseria meningitidis Outer Membrane Vesicles (OMV) to induce protective
responses in humans is well established and mainly attributed to Porin A (PorA). However …

Due to the continuing emergence of multidrug resistant strains of Neisseria gonorrhoeae
there is an urgent need for the development of a gonococcal vaccine. We evaluated the …

Patients receiving eculizumab have an increased risk for meningococcal disease, but most
reported cases are attributable to encapsulated meningococcal strains. We describe a case …

ABSTRACT MenB-4C (Bexsero; GlaxoSmithKline Biologicals) is a licensed meningococcal
vaccine for capsular B strains. The vaccine contains detergent-extracted outer membrane …

Neisseria meningitidis, the causative agent of invasive meningococcal disease (IMD), is
classified into different serogroups defined by their polysaccharide capsules. Meningococcal …

Abstract The 4CMenB (BexseroR) vaccine contains detergent-extracted outer membrane
vesicles (OMVs) from a Neisseria meningitidis (Nm) group B strain NZ98/254 and three …