Phenothiazines (PTZ) are antipsychotics known to modulate a variety of neurotransmitter
activities that include dopaminergic and cholinergic signaling and have been identified as …

Rhodium-catalyzed regiodivergent [3+ 2] and [5+ 2] cycloadditions of quinolinium ylides with
alkynes are reported, providing highly functionalized five-membered indolizine derivatives …

Abstract The formal [3+ 2] dipolar cycloaddition (or annulation) of donor‐acceptor
cyclopropanoate esters with pyridines and 5‐nitroquinoline is reported. Electron‐deficient …

A new family of microtubule-targeting agents with a phenothiazine A-ring was synthesized
and evaluated for anti-proliferative activity and interaction with tubulin. These new …

In this review we systematized the theoretical and experimental data concerning the
versatile approaches for the synthesis of N-acylphenothiazines. The aim of the study was to …

Pyrrolo [2, 1-a] isoquinoline derivatives were synthesized by one-pot three-component
reactions starting from isoquinoline, 2-bromoacetophenones and different non-symmetrical …

Two new families of human farnesyltransferase inhibitors 13a–m and 14a–d, based on a
phenothiazine scaffold, were synthesized. Compounds 14a and 14b were the most …

Cycloaddition reactions of azomethine ylides are the most direct way to synthesise
pyrrolidine derivatives. They have been studied for several decades and have become an …

The synthesis of various 1, 3-dithiolium salts has been accomplished through a combined
procedure of acid catalyzed cyclocondensation of various substituted 2-(2-hydroxyphenyl)-1 …

Abstract New pyrrolo [2, 1‐a] isoquinolines were obtained by two one‐pot procedures via 1,
3‐dipolar cycloaddition between the isoquinolinium N‐ylides and symmetrical acetylenic …