The large GTP ase dynamin is the first protein shown to catalyze membrane fission.
Dynamin and its related proteins are essential to many cell functions, from endocytosis to …

Helical constructs are ubiquitous in nature at all size domains, from molecular to
macroscopic. The helical topology confers unique mechanical functions that activate certain …

Dynamin is a mechanochemical GTPase that oligomerizes around the neck of clathrin-
coated pits and catalyses vesicle scission in a GTP-hydrolysis-dependent manner. The …

The GTPase dynamin polymerizes into a helical coat that constricts membrane necks of
endocytic pits to promote their fission. However, the dynamin mechanism is still debated …

In eukaryotic cells, membrane compartments are split into two by membrane fission. This
ensures discontinuity of membrane containers and thus proper compartmentalization. The …

Membrane-bound transport carriers are used to transfer cargo between membranes of the
secretory and the endocytic pathways. The generation of these carriers can be classified into …

Biological membranes constitute boundaries of cells and cell organelles. These membranes
are soft fluid interfaces whose thermodynamic states are dictated by bending moduli …

We studied the single-molecule photo-switching properties of Dronpa, a green photo-
switchable fluorescent protein and a popular marker for photoactivated localization …

Membrane fission is essential to life. It is required for many fundamental cellular processes,
as diverse as cyto-and karyokinesis, organelle division, membrane repair, and membrane …

Dynamin is a dimeric GTPase that assembles into a helix around the neck of endocytic buds.
Upon GTP hydrolysis, dynamin breaks these necks, a reaction called membrane fission …