Chronic low-level polychlorinated biphenyl (PCB) exposures remain a significant public
health concern since results from epidemiological studies indicate that PCB burden is …

In this review we will attempt to summarise the complex and sometimes contradictory effects
that mitochondria have on different forms of calcium signalling. Mitochondria can influence …

Aggregation of α‐synuclein is a hallmark of Parkinson's disease and dementia with Lewy
bodies. We here investigate the relationship between cytosolic Ca2+ and α‐synuclein …

Parthanatos is a new form of programmed cell death. It has been recognized to be critical in
cerebral ischemia–reperfusion injury, and reactive oxygen species (ROS) can induce …

purpose. Disruption in intracellular calcium ion (Ca 2+) homeostasis has major effects on
health. Persistent Ca 2+ overload induces mitochondrial permeability transition pore (MPTP) …

Traumatic brain injury (TBI) refers to brain damage resulting from external mechanical force,
such as a blast or crash. Our current understanding of TBI is derived mainly from in vivo …

Rheumatic diseases, such as osteoarthritis and rheumatoid arthritis, affect over 750 million
people worldwide and contribute to approximately 40% of chronic pain cases. Inflammation …

Neuropathological models and neurological disease progression and treatments have
always been of great interest in biomedical research because of their impact on society. The …

Rheumatic diseases, such as osteoarthritis and rheumatoid arthritis, affect over 750 million
people worldwide and contribute to approximately 40% of chronic pain cases. Inflammation …

Capsaicin is an ingredient in spicy peppers that produces burning pain by activating
transient receptor potential vanilloid 1 (TRPV1), a Ca 2+-permeable ion channel in …