The inflammation is the protective response of the body against various harmful stimuli;
however, the aberrant and inappropriate activation tends to become harmful. The acute …

Nrf2 is a transcription factor that stimulates the expression of genes which have antioxidant
response element-like sequences in their promoter. Nrf2 is a cellular protector, and this …

In 2018, 550,000 people were diagnosed with bladder cancer (BC), of which nearly 200,000
people died. Moreover, men are 4 times more likely than women to be diagnosed with BC …

Pancreatic cancer (PC) is one of the most fatal diseases with a very high rate of metastasis
and low rate of survival. Despite the advances in understanding this devastating disease …

Transforming growth factor-β (TGF-β) mediates numerous biological processes, including
embryonic development and the maintenance of cellular homeostasis in a context …

Pancreatitis is a serious effect of the heavy metal cadmium (Cd) and inflammation and
oxidative stress (OS) are implicated in Cd-induced pancreatic injury. This study evaluated …

Pancreatic tumors are a serious health problem with a 7% mortality rate worldwide.
Inflammatory processes and oxidative stress play important roles in the development of …

Cardiovascular complications induced by high fat are one of the most challenging health
problems presently. Oxidative stress, inflammation and fibrosis are major components …

Chemoresistance is a leading cause of morbidity and mortality in patients with pancreatic
cancer and remains an obstacle to successful treatment. The antioxidant transcription factor …

Severe acute pancreatitis (SAP) is a digestive system disease that is associated with a
range of complications including intestinal dysfunction. In this study, we determined that the …