Strong associations of serum selenoprotein P with all-cause mortality and mortality due to cancer, cardiovascular, respiratory and gastrointestinal diseases in older …

B Schöttker, B Holleczek, S Hybsier, J Köhrle… - European journal of …, 2024 - Springer
Background Selenium is an essential trace mineral. The main function of selenoprotein P
(SELENOP) is to transport selenium but it has also been ascribed anti-oxidative effects …

The causal relationship between genetically predicted blood metabolites and idiopathic pulmonary fibrosis: A bidirectional two-sample Mendelian randomization study

T Pan, L Bai, D Zhu, Y Wei, Q Zhao, F Feng, Z Wang… - Plos one, 2024 - journals.plos.org
Background Numerous metabolomic studies have confirmed the pivotal role of metabolic
abnormalities in the development of idiopathic pulmonary fibrosis (IPF). Nevertheless, there …

Ferroptosis in schizophrenia: Mechanisms and therapeutic potentials

S Lv, C Luo - Molecular Medicine Reports, 2024 - spandidos-publications.com
Schizophrenia, a complex psychiatric disorder, presents with multifaceted symptoms and
important challenges in treatment, primarily due to its pathophysiological complexity, which …

Unraveling the Link: Mendelian Randomization Reveals Causal Relationship Between Selenium and Metabolic Syndrome

F Liu, K Wang, J Nie, MG Deng - Biological Trace Element Research, 2024 - Springer
Observational studies have linked selenium and metabolic syndrome (MetS), but the
causality remains unclear. Therefore, this study intends to determine the causal relationship …

The causal effect of iron status on risk of anxiety disorders: A two-sample Mendelian randomization study

R Yin, Q Gao, G Fu, Q Zhao - Plos one, 2024 - journals.plos.org
Objectives Observational studies had investigated the association of iron metabolism with
anxiety disorders. The conclusions were inconsistent and not available to reveal the causal …

The causal effects between selenium levels and the brain cortical structure: A two‐sample Mendelian randomization study

X Zhang, Y Zhong, K He - Brain and Behavior, 2023 - Wiley Online Library
Extensive research has demonstrated the critical role of selenium (Se) and selenoproteins in
brain function and cognition. However, the impact of Se on brain cortical structure remains …

Association of circulating minerals and vitamins with pregnancy complications: a Mendelian randomization study

Y Xie, J Zhang, S Ni, J Li - Frontiers in Nutrition, 2024 - frontiersin.org
Background: Though considerable studies suggesting connections between micronutrients
and pregnancy complications, current evidence remains inconsistent and lacks causative …

Relationship between mental disorders and abdominal aortic aneurysm: insights from genetic perspectives

MG Deng, C Chai, K Wang, JQ Nie, F Liu, Y Liang… - medRxiv, 2024 - medrxiv.org
Objective: To explore the correlation or potential causation between mental disorders
[depression, schizophrenia (SCZ), bipolar disorder (BIP)], and abdominal aortic aneurysm …

Investigating the causal and genetic relationship between migraine and Parkinson's disease

MG Deng, X Zhou, F Liu, K Wang, L Luo… - … : The Journal of Head … - Wiley Online Library
Objective The relationship between migraine and Parkinson's disease (PD) remains
controversial. We aimed to investigate the causal and genetic associations between …

The Relationship Between Frailty and Schizophrenia: A Genetic Association and Mendelian Randomization Study

MG Deng, K Wang, F Liu, X Zhou, J Liu - 2023 - researchsquare.com
Results The global genetic correlation analyses presented they were positively associated,
and the local genetic correlation analyses demonstrated they were locally correlated in three …