Introduction Previous research has shown that statin adherence for the primary prevention of
CVD is lower compared to secondary prevention populations. Therefore the aim of this …

Extensive research has demonstrated the efficacy of the LCD to improve the most robust
CVD risk factors, such as hyperglycemia, hypertension, and atherogenic dyslipidemia. Our …

Cholesterol metabolism operates autonomously within the central nervous system (CNS),
where the majority of cholesterol resides in myelin. We demonstrate that TDP-43, the …

Background Premorbid body mass index, physical activity, diabetes and cardiovascular
disease have been associated with an altered risk of developing amyotrophic lateral …

Objectives The relevant data about the effects and the associated mechanisms of statins on
muscle strength and physical capacity is inconsistent. We investigated the potential …

Amyotrophic lateral sclerosis is a progressive and fatal neurodegenerative disease typically
presenting with bulbar or limb weakness. There is increasing evidence that amyotrophic …

Flavonoids, especially their inhibitory effect on DPP-IV activity, have been widely recognized
for their antidiabetic effects. However, the variety of natural flavonoid derivatives is very rich …

Background: Observational studies suggest that statins may affect amyotrophic lateral
sclerosis (ALS). However, they are limited by confounding and reverse causality biases …

Introduction Amyotrophic lateral sclerosis is a fatal progressive disease with a still unclear
multi-factorial etiology. This study focused on the potential relationship between drug …

Background Medications that are used for treatment of metabolic disorders have been
suggested to be associated with the development of amyotrophic lateral sclerosis (ALS) …