Tolerance and resistance of microbial biofilms
Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …
Photocatalytic antimicrobials: principles, design strategies, and applications
B Ran, L Ran, Z Wang, J Liao, D Li, K Chen… - Chemical …, 2023 - ACS Publications
Nowadays, the increasing emergence of antibiotic-resistant pathogenic microorganisms
requires the search for alternative methods that do not cause drug resistance. Phototherapy …
requires the search for alternative methods that do not cause drug resistance. Phototherapy …
[HTML][HTML] Antimicrobial resistance: Prevalence, economic burden, mechanisms of resistance and strategies to overcome
Antibiotic resistance is a major health concern globally and has been estimated to cause 10
million deaths worldwide by year 2050 if the current trend of inappropriate and excessive …
million deaths worldwide by year 2050 if the current trend of inappropriate and excessive …
Bacterial defences: mechanisms, evolution and antimicrobial resistance
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …
microorganisms, including competing bacteria, bacteriophages and predators. In response …
Antidepressants can induce mutation and enhance persistence toward multiple antibiotics
Antibiotic resistance is an urgent threat to global health. Antidepressants are consumed in
large quantities, with a similar pharmaceutical market share (4.8%) to antibiotics (5%). While …
large quantities, with a similar pharmaceutical market share (4.8%) to antibiotics (5%). While …
[HTML][HTML] Streptomyces: The biofactory of secondary metabolites
Natural products derived from microorganisms serve as a vital resource of valuable
pharmaceuticals and therapeutic agents. Streptomyces is the most ubiquitous bacterial …
pharmaceuticals and therapeutic agents. Streptomyces is the most ubiquitous bacterial …
Fluoroquinolone antibiotics: Occurrence, mode of action, resistance, environmental detection, and remediation–A comprehensive review
S Bhatt, S Chatterjee - Environmental Pollution, 2022 - Elsevier
Antibiotics play an essential role in the medical healthcare world, but their widespread
usage and high prevalence have posed negative environmental consequences. During the …
usage and high prevalence have posed negative environmental consequences. During the …
Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
[HTML][HTML] Antibiotics in the clinical pipeline as of December 2022
The need for new antibacterial drugs to treat the increasing global prevalence of drug-
resistant bacterial infections has clearly attracted global attention, with a range of existing …
resistant bacterial infections has clearly attracted global attention, with a range of existing …
[HTML][HTML] A deep learning approach to antibiotic discovery
Due to the rapid emergence of antibiotic-resistant bacteria, there is a growing need to
discover new antibiotics. To address this challenge, we trained a deep neural network …
discover new antibiotics. To address this challenge, we trained a deep neural network …