3D bioprinting of tissues and organs

SV Murphy, A Atala - Nature biotechnology, 2014 - nature.com
Additive manufacturing, otherwise known as three-dimensional (3D) printing, is driving
major innovations in many areas, such as engineering, manufacturing, art, education and …

3D bioprinting in tissue engineering for medical applications: the classic and the hybrid

Z Xie, M Gao, AO Lobo, TJ Webster - Polymers, 2020 - mdpi.com
Three-dimensional (3D) printing, as one of the most popular recent additive manufacturing
processes, has shown strong potential for the fabrication of biostructures in the field of tissue …

Design, clinical translation and immunological response of biomaterials in regenerative medicine

K Sadtler, A Singh, MT Wolf, X Wang… - Nature Reviews …, 2016 - nature.com
The field of regenerative medicine aims to replace tissues lost as a consequence of disease,
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …

Microscale technologies for tissue engineering and biology

A Khademhosseini, R Langer… - Proceedings of the …, 2006 - National Acad Sciences
Microscale technologies are emerging as powerful tools for tissue engineering and
biological studies. In this review, we present an overview of these technologies in various …

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

S Santaguida, A Tighe, AM D'Alise, SS Taylor… - Journal of Cell …, 2010 - rupress.org
The catalytic activity of the MPS1 kinase is crucial for the spindle assembly checkpoint and
for chromosome biorientation on the mitotic spindle. We report that the small molecule …

[HTML][HTML] A combined chemical and genetic approach for the generation of induced pluripotent stem cells

Y Shi, JT Do, C Desponts, HS Hahm, HR Schöler… - Cell stem cell, 2008 - cell.com
Recent breakthroughs in using viral transduction of a few genes for the reprogramming of
both mouse and human somatic cells into induced pluripotent stem (iPS) cells have opened …

Mesenchymal stem cells: isolation, in vitro expansion and characterization

N Beyer Nardi, L da Silva Meirelles - Stem cells, 2006 - Springer
Mesenchymal stem cells (MSC), one type of adult stem cell, are easy to isolate, culture, and
manipulate in ex vivo culture. These cells have great plasticity and the potential for …

Diversity-oriented synthesis: exploring the intersections between chemistry and biology

DS Tan - Nature chemical biology, 2005 - nature.com
Diversity-oriented synthesis (DOS) is an emerging field involving the synthesis of
combinatorial libraries of diverse small molecules for biological screening. Rather than …

Mature adipocyte‐derived dedifferentiated fat cells exhibit multilineage potential

T Matsumoto, K Kano, D Kondo… - Journal of cellular …, 2008 - Wiley Online Library
When mature adipocytes are subjected to an in vitro dedifferentiation strategy referred to as
ceiling culture, these mature adipocytes can revert to a more primitive phenotype and gain …

The purines: Potent and versatile small molecule inhibitors and modulators of key biological targets

M Legraverend, DS Grierson - Bioorganic & medicinal chemistry, 2006 - Elsevier
The goal of this review is to highlight the wide range of biological activities displayed by
purines, with particular emphasis on new purine-based agents which find potential …