Surface modification using phosphonic acids and esters

C Queffélec, M Petit, P Janvier, DA Knight… - Chemical …, 2012 - ACS Publications
1. INTRODUCTION The design of organically modified surfaces is a rapidly expanding field
of research in materials science in which the central purpose is access to materials …

Protein chip technology

H Zhu, M Snyder - Current opinion in chemical biology, 2003 - Elsevier
Microarray technology has become a crucial tool for large-scale and high-throughput
biology. It allows fast, easy and parallel detection of thousands of addressable elements in a …

Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes

CT Garnett, C Palena, M Chakarborty, KY Tsang… - Cancer research, 2004 - AACR
Local radiation of tumor masses is an established modality for the therapy of a range of
human tumors. It has recently been recognized that doses of radiation, lower than or equal …

Protein microarrays and proteomics

G MacBeath - Nature genetics, 2002 - nature.com
The system-wide study of proteins presents an exciting challenge in this information-rich age
of whole-genome biology. Although traditional investigations have yielded abundant …

α-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer

MA Rubin, M Zhou, SM Dhanasekaran, S Varambally… - Jama, 2002 - jamanetwork.com
ContextMolecular profiling of prostate cancer has led to the identification of candidate
biomarkers and regulatory genes. Discoveries from these genome-scale approaches may …

Protein analysis on a proteomic scale

E Phizicky, PIH Bastiaens, H Zhu, M Snyder, S Fields - Nature, 2003 - nature.com
The long-term challenge of proteomics is enormous: to define the identities, quantities,
structures and functions of complete complements of proteins, and to characterize how these …

Clinical proteomics: translating benchside promise into bedside reality

EF Petricoin, KC Zoon, EC Kohn, JC Barrett… - Nature reviews Drug …, 2002 - nature.com
The ultimate goal of proteomics is to characterize the information flow through protein
networks. This information can be a cause, or a consequence, of disease processes. Clinical …

Protein microarray technology

DA Hall, J Ptacek, M Snyder - Mechanisms of ageing and development, 2007 - Elsevier
Protein chips have emerged as a promising approach for a wide variety of applications
including the identification of protein–protein interactions, protein–phospholipid interactions …

[HTML][HTML] Protein microarrays: meeting analytical challenges for clinical applications

LA Liotta, V Espina, AI Mehta, V Calvert, K Rosenblatt… - Cancer cell, 2003 - cell.com
Protein microarrays, one emerging class of proteomic technologies, have broad applications
for discovery and quantitative analysis. A rapidly expanding use of this technology is the …

Protein microarrays: prospects and problems

T Kodadek - Chemistry & biology, 2001 - cell.com
Protein microarrays are potentially powerful tools in biochemistry and molecular biology.
Two types of protein microarrays are defined. One, termed a protein function array, will …