[HTML][HTML] Neuronal excitation/inhibition imbalance: core element of a translational perspective on Alzheimer pathophysiology

F Maestú, W de Haan, MA Busche, J DeFelipe - Ageing Research Reviews, 2021 - Elsevier
Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …

[HTML][HTML] The virtual epileptic patient: individualized whole-brain models of epilepsy spread

VK Jirsa, T Proix, D Perdikis, MM Woodman, H Wang… - Neuroimage, 2017 - Elsevier
Individual variability has clear effects upon the outcome of therapies and treatment
approaches. The customization of healthcare options to the individual patient should …

Breaking the boundaries of interacting with the human brain using adaptive closed-loop stimulation

K Nasr, D Haslacher, E Dayan, N Censor… - Progress in …, 2022 - Elsevier
The human brain is arguably one of the most complex systems in nature. To understand how
it operates, it is essential to understand the link between neural activity and behavior …

The Bayesian Virtual Epileptic Patient: A probabilistic framework designed to infer the spatial map of epileptogenicity in a personalized large-scale brain model of …

M Hashemi, AN Vattikonda, V Sip, M Guye… - NeuroImage, 2020 - Elsevier
Despite the importance and frequent use of Bayesian frameworks in brain network modeling
for parameter inference and model prediction, the advanced sampling algorithms …

Multi-scale account of the network structure of macaque visual cortex

M Schmidt, R Bakker, CC Hilgetag, M Diesmann… - Brain Structure and …, 2018 - Springer
Cortical network structure has been extensively characterized at the level of local circuits
and in terms of long-range connectivity, but seldom in a manner that integrates both of these …

[HTML][HTML] Modeling brain dynamics after tumor resection using The Virtual Brain

H Aerts, M Schirner, T Dhollander, B Jeurissen… - Neuroimage, 2020 - Elsevier
Brain tumor patients scheduled for tumor resection often face significant uncertainty, as the
outcome of neurosurgery is difficult to predict at the individual patient level. Recently …

Neural mechanisms underlying human auditory evoked responses revealed by human neocortical neurosolver

C Kohl, T Parviainen, SR Jones - Brain topography, 2022 - Springer
Auditory evoked fields (AEFs) are commonly studied, yet their underlying neural
mechanisms remain poorly understood. Here, we used the biophysical modelling software …

[HTML][HTML] BOLD signal variability and complexity in children and adolescents with and without autism spectrum disorder

AK Easson, AR McIntosh - Developmental cognitive neuroscience, 2019 - Elsevier
Variability of neural signaling is an important index of healthy brain functioning, as is signal
complexity, which relates to information processing capacity. Alterations in variability and …

Estimation and validation of individualized dynamic brain models with resting state fMRI

MF Singh, TS Braver, MW Cole, SN Ching - NeuroImage, 2020 - Elsevier
A key challenge for neuroscience is to develop generative, causal models of the human
nervous system in an individualized, data-driven manner. Previous initiatives have either …

[HTML][HTML] Structural and functional, empirical and modeled connectivity in the cerebral cortex of the rat

A Diaz-Parra, Z Osborn, S Canals, D Moratal, O Sporns - Neuroimage, 2017 - Elsevier
Connectomics data from animal models provide an invaluable opportunity to reveal the
complex interplay between structure and function in the mammalian brain. In this work, we …