The vertebrate transcription factor NF-κB is induced by over 150 different stimuli. Active NF-
κB, in turn, participates in the control of transcription of over 150 target genes. Because a …

Transcription factors of the Rel/NF-κB family are activated in response to signals that lead to
cell growth, differentiation, and apoptosis, and these proteins are critical elements involved …

Post‐translational activation of the higher eukaryotic transcription factor NF‐kappa B
requires both phosphorylation and proteolytic degradation of the inhibitory subunit I kappa B …

Publisher Summary This chapter highlights NF-кB/Rel protein complex. Associations of the
binding and regulatory subunits of NF-кB operate at the center of a variety of different signal …

During the development of an organism different patterns of active genes are established in
the nuclei of differentiating cells. These specific gene patterns are translated into distinct …

The possibility that bacteria may have evolved strategies to overcome host cell apoptosis
was explored by using Rickettsia rickettsii, an obligate intracellular Gram-negative bacteria …

▪ Abstract Theileria parva and T. annulata provide intriguing models for the study of parasite-
host interactions. Both parasites possess the unique property of being able to transform the …

The secretion of the T cell growth factor Interleukin 2 (IL-2) is a key event in the activation of
T lymphocytes. IL-2 triggers peripheral T lymphocytes to enter the S phase of the cell cycle …

Protozoan parasites which reside inside a host cell avoid direct destruction by the immune
system of the host. The infected cell, however, still has the capacity to counteract the …

▪ Abstract Lentiviruses are associated with chronic diseases of the hematological and
neurological systems in animals and man. In particular, human immunodeficiency virus type …