Astrocytes are no longer seen as a homogenous population of cells. In fact, recent studies
indicate that astrocytes are morphologically and functionally diverse and play critical roles in …

Epilepsies are chronic neurological diseases that affect approximately 2% of the world
population. In addition to being one of the most frequent neurological disorders, treatment …

Astrocyte maturation is crucial to proper brain development and function. This maturation
process includes the ramification of astrocytic morphology and the establishment of …

Objective To examine antioxidative system in hippocampi of patients with mesial temporal
lobe epilepsy associated with hippocampal sclerosis (mTLE‐HS). Methods Activity and …

Background Proteomic analysis of cerebrospinal fluid (CSF) has shown great promise in
identifying potential markers of injury in neurodegenerative diseases 1, 2, 3, 4, 5, 6, 7, 8, 9 …

Epilepsy is a common neurological disorder, which is not well understood at the molecular
level. Exactly why some brain regions produce epileptic discharges and others do not is not …

Carbonic anhydrase I (CA1) is the cytosolic isoform of mammalian α-CA family members
which are responsible for maintaining pH homeostasis in the physiology and pathology of …

Summary Objective Astrocytic inclusions (AIs) have been identified on histologic specimens
of patients with early onset seizures, and the proteomic contents have been described. The …

Objectives Cerebral hyaline protoplasmic astrocytopathy (HPA) is a clinicopathologic entity
characterized by eosinophilic cytoplasmic inclusions within astrocytes. It has been observed …

Although rare, hyaline cytoplasmic inclusions isolated to astrocytes of the cerebral cortex
have been identified in a spectrum of diseases ranging from intractable epilepsy in pediatric …