Mechanism of the antidiabetic action of Nigella sativa and Thymoquinone: a review

A Shaukat, A Zaidi, H Anwar, N Kizilbash - Frontiers in Nutrition, 2023 - frontiersin.org
Introduction Long used in traditional medicine, Nigella sativa (NS; Ranunculaceae) has
shown significant efficacy as an adjuvant therapy for diabetes mellitus (DM) management by …

Quality of oil extracted by cold press from Nigella sativa seeds incorporated with rosemary extracts and pretreated by microwaves

A Ashrafi, S Azadmard-Damirchi… - Green Processing and …, 2023 - degruyter.com
Black cumin (Nigella sativa) seed (BS) oil has high a peroxide value (PV) and acid value
(AV). In this study, BS was incorporated with different levels of rosemary extracts as a natural …

The Use of Nigella sativa in Cardiometabolic Diseases

G Derosa, A D'Angelo, P Maffioli, L Cucinella… - Biomedicines, 2024 - mdpi.com
Nigella sativa L. is an herb that is commonly used in cooking and in traditional medicine,
particularly in Arab countries, the Indian subcontinent, and some areas of eastern Europe …

Optimizing the encapsulation of black seed oil into alginate beads by ionic gelation

H Alkhatib, E Assadpour, ASM Sabere… - Journal of Food …, 2022 - Elsevier
Black seed oil (BSO) has various therapeutics effects; however, its unpleasant taste and
restricted availability in the market in the form of raw oil or soft/hard gelatine capsules …

Effect of refining on the quality of oils extracted by cold press from black cumin (Nigella sativa L.) seed and by solvent from its cake

S Abedinzadeh, M Torbati… - … Journal of Food …, 2023 - academic.oup.com
Black cumin seed oil, known for its bioactive compounds and health benefits, faces
challenges due to its high peroxide value and free fatty acid content, limiting its applications …

Screening of Thymoquinone Content in Commercial Nigella sativa Products to Identify a Promising and Safe Study Medication

E Khaikin, S Chrubasik-Hausmann, S Kaya… - Nutrients, 2022 - mdpi.com
(1) Background: Thymoquinone (TQ) is the leading compound accounting for the
pharmacological effects of Nigella sativa seed oil, also known as black seed oil. This study …

[HTML][HTML] Thymoquinone Pectin Beads Produced via Electrospray: Enhancing Oral Targeted Delivery for Colorectal Cancer Therapy

M Alfatama, H Choukaife, O Al Rahal, NZM Zin - Pharmaceutics, 2024 - mdpi.com
Background/Objectives: Thymoquinone (TQ) exhibits diverse biological activities, but its
poor solubility and bioavailability limit its cancer efficacy, requiring innovative solutions. This …

Pilot scale manufacturing of black seed oil-loaded alginate beads; process development, and stability of thymoquinone

H Alkhatib, F Mohamed, M Alfatama, E Assadpour… - Heliyon, 2024 - cell.com
The approach of ionic gelation was employed at the pilot scale of the 50 kg batch size to
manufacture black seed oil (BSO)-loaded alginate (ALG) beads as a natural source …

Changes in the quality of oil extracted by hot pressing from black cumin (Nigella sativa) seeds and by solvent from the obtained cake during refining

S Abedinzadeh, M Torbati… - Food Science & …, 2024 - Wiley Online Library
In this study, oil was extracted from black cumin (Nigella sativa) seed (BCS) by press, and oil
was extracted from the obtained cake with a solvent. The changes in the quality of both …

[HTML][HTML] Variation in the Composition and Quality of Nigella sativa L. Seed Oils—The Underestimated Impact on Possible Health-Promoting Properties

G Dąbrowski, S Czaplicki, I Konopka - Molecules, 2024 - mdpi.com
Nigella sativa L.(black cumin) is one of the most investigated medicinal plants in recent
years. Volatile compounds like thymoquinone and unsaponifiable lipid compounds are …