Resolving clinical phenotypes into endotypes in allergy: molecular and omics approaches

TB Mersha, Y Afanador, E Johansson… - Clinical reviews in …, 2021 - Springer
Allergic diseases are highly complex with respect to pathogenesis, inflammation, and
response to treatment. Current efforts for allergic disease diagnosis have focused on clinical …

Laser capture microdissection as a method for investigating the human hair follicle microbiome reveals region-specific differences in the bacteriome profile

MB Lousada, J Edelkamp, T Lachnit, M Fehrholz… - BMC Research …, 2023 - Springer
Abstract Objective Human hair follicles (HFs) are populated by a rich and diverse
microbiome, traditionally evaluated by methods that inadvertently sample the skin …

Cell-intrinsic differences between human airway epithelial cells from children and adults

EF Maughan, RE Hynds, A Pennycuick, E Nigro… - Iscience, 2022 - cell.com
The airway epithelium is a protective barrier that is maintained by the self-renewal and
differentiation of basal stem cells. Increasing age is a principle risk factor for chronic lung …