Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-
TB) continue to challenge physicians and public health specialists. Global treatment …

Background and aim Tuberculosis (TB) is associated with a high mortality in the intensive
care unit (ICU), especially in subjects with Acute Respiratory Distress Syndrome (ARDS) …

The vast majority of marketed drugs are orally administrated. As such, drug absorption is
one of the important drug metabolism and pharmacokinetics parameters that should be …

This document is the result of the deliberations of the Committee on Emerging Pathogens
and COVID-19 of the Illustrious Official College of Physicians of Madrid (ICOMEM) regarding …

According to World Health Organization estimates, tuberculosis (TB) and lower respiratory
tract infections (LRTIs) are both among the top 10 global causes of death. TB and community …

Among critically ill patients, severe pulmonary and extrapulmonary tuberculosis has high
morbidity and mortality. Yet, it is a diagnostic challenge given its nonspecific clinical …

Purpose This study aimed to analyze data from the Extracorporeal Life Support Organization
(ELSO) registry to elucidate the epidemiology and outcomes of patients with tuberculosis …

BACKGROUND: Extrapulmonary TB (EPTB) is more difficult to diagnose than pulmonary TB.
The delayed management of EPTB can lead to complications and increase the socio …

Abstract Background The detection of Mycobacterium tuberculosis (MTB) in the intensive
care unit (ICU) presents several challenges, mainly associated to the clinical state of the …

Objectives Critically ill patients with tuberculosis (TB) face a high mortality risk and require
effective treatment. There is a paucity of data on rifampicin pharmacokinetics, the impact of …