Spike glycoprotein-mediated entry of SARS coronaviruses
L Wang, Y Xiang - Viruses, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 are
enveloped, positive-sense, single-stranded RNA viruses and causes of epidemic diseases …
enveloped, positive-sense, single-stranded RNA viruses and causes of epidemic diseases …
[HTML][HTML] Possible mechanisms of cholesterol elevation aggravating COVID-19
Y Tang, L Hu, Y Liu, B Zhou, X Qin, J Ye… - … journal of medical …, 2021 - ncbi.nlm.nih.gov
Importance: Despite the availability of a vaccine against the severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2), humans will have to live with this virus and the after …
syndrome-coronavirus-2 (SARS-CoV-2), humans will have to live with this virus and the after …
Characterization of critical determinants of ACE2–SARS CoV-2 RBD interaction
Despite sequence similarity to SARS-CoV-1, SARS-CoV-2 has demonstrated greater
widespread virulence and unique challenges to researchers aiming to study its …
widespread virulence and unique challenges to researchers aiming to study its …
A trimeric hydrophobic zipper mediates the intramembrane assembly of SARS-CoV-2 spike
Q Fu, JJ Chou - Journal of the American Chemical Society, 2021 - ACS Publications
The S protein of SARS-CoV-2 is a type I membrane protein that mediates membrane fusion
and viral entry. A vast amount of structural information is available for the ectodomain of S, a …
and viral entry. A vast amount of structural information is available for the ectodomain of S, a …
SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition
As the COVID-19 pandemic continues, there is an imminent need for rapid diagnostic tools
and effective antivirals targeting SARS-CoV-2. We have developed a novel …
and effective antivirals targeting SARS-CoV-2. We have developed a novel …
Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to …
D Pflumm, A Seidel, F Klein, R Groß, L Krutzke… - Frontiers in …, 2023 - frontiersin.org
A multitude of alterations in the old immune system impair its functional integrity. Closely
related, older individuals show, for example, a reduced responsiveness to severe acute …
related, older individuals show, for example, a reduced responsiveness to severe acute …
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry
The ongoing COVID-19 pandemic has highlighted the immediate need for the development
of antiviral therapeutics targeting different stages of the SARS-CoV-2 life cycle. We …
of antiviral therapeutics targeting different stages of the SARS-CoV-2 life cycle. We …
A luciferase based automated assay for rapid and sensitive detection of SARS-CoV-2 antibodies
W Zhou, P He, H Liu, H Wei, J Yu - Analytica chimica acta, 2023 - Elsevier
Abstract The Coronavirus disease 2019 (COVID-19) pandemic brings great challenges to
the public health and social economics around the world. As the pandemic continues and …
the public health and social economics around the world. As the pandemic continues and …
Modeling receptor motility along advecting lipid membranes
This work aims to overview multiphysics mechanobiological computational models for
receptor dynamics along advecting cell membranes. Continuum and statistical models of …
receptor dynamics along advecting cell membranes. Continuum and statistical models of …
Secondary structures of the transmembrane domain of SARS-CoV-2 spike protein in detergent micelles
Q Li, Q Huang, C Kang - International Journal of Molecular Sciences, 2022 - mdpi.com
Spike protein of SARS-CoV-2 contains a single-span transmembrane (TM) domain and
plays roles in receptor binding, viral attachment and viral entry to the host cells. The TM …
plays roles in receptor binding, viral attachment and viral entry to the host cells. The TM …