Melatonin: reducing the toxicity and increasing the efficacy of drugs
Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine) is a molecule with a very wide
phylogenetic distribution from plants to man. In vertebrates, melatonin was initially thought to …
phylogenetic distribution from plants to man. In vertebrates, melatonin was initially thought to …
Cyclooxygenase 2—implications on maintenance of gastric mucosal integrity and ulcer healing: controversial issues and perspectives
F Halter, AS Tarnawski, A Schmassmann, BM Peskar - Gut, 2001 - gut.bmj.com
Cyclooxygenase (COX), the key enzyme for synthesis of prostaglandins, exists in two
isoforms (COX-1 and COX-2). COX-1 is constitutively expressed in the gastrointestinal tract …
isoforms (COX-1 and COX-2). COX-1 is constitutively expressed in the gastrointestinal tract …
Antiulcerogenic effect of some gastrointestinally acting plant extracts and their combination
MT Khayyal, MA El-Ghazaly, SA Kenawy… - …, 2001 - thieme-connect.com
Extracts from the plants Iberis amara, Melissa officinalis, Matricaria recutita, Carum carvi,
Mentha× piperita, Glycyrrhtza glabra, Angelica archangelica, S-lybum marianum and …
Mentha× piperita, Glycyrrhtza glabra, Angelica archangelica, S-lybum marianum and …
The potential of melatonin in reducing morbidity–mortality after craniocerebral trauma
MD Maldonado, F Murillo‐Cabezas… - Journal of pineal …, 2007 - Wiley Online Library
Craniocerebral trauma (CCT) is the most frequent cause of morbidity–mortality as a result of
an accident. The probable origins and etiologies are multifactorial and include free radical …
an accident. The probable origins and etiologies are multifactorial and include free radical …
Inhibitory effect of non-steroidal anti-inflammatory drugs on mucosal cell proliferation associated with gastric ulcer healing
S Levi, MJ Walport, HJF Hodgson, RA Goodlad… - The Lancet, 1990 - Elsevier
To find out whether non-steroidial anti-inflammatory drugs (NSAIDs) inhibit the proliferation
of mucosal cells that normally leads to healing of gastric ulcers a microdissection technique …
of mucosal cells that normally leads to healing of gastric ulcers a microdissection technique …
Protective effect of famotidine, omeprazole, and melatonin against acetylsalicylic acid-induced gastric damage in rats
G Şener-Muratoğlu, K Paskaloğlu, S Arbak… - Digestive diseases and …, 2001 - Springer
It has been reported that both omeprazole and famotidine have a protective effect against
gastric mucosal damage induced by acetylsalicylic acid (ASA) and other nonsteroidal …
gastric mucosal damage induced by acetylsalicylic acid (ASA) and other nonsteroidal …
Anti‐ulcerogenic effect of chitin and chitosan on mucosal antioxidant defence system in HCl‐ethanol‐induced ulcer in rats
The anti‐ulcerogenic effect of chitin and chitosan against ulcer induced by HCl‐ethanol in
male Wistar rats was studied. Levels of acid output, pepsin, protein, lipid peroxides and …
male Wistar rats was studied. Levels of acid output, pepsin, protein, lipid peroxides and …
'Healed'experimental gastric ulcers remain histologically and ultrastructurally abnormal
A Tarnawski, D Hollander, WJ Krause… - Journal of clinical …, 1990 - journals.lww.com
The present study was designed to assess histologic and iltrastructural features of gastric
mucosa in the areas of rossly healed ulcers (acetic acid-induced gastric ulcers) in ats. The …
mucosa in the areas of rossly healed ulcers (acetic acid-induced gastric ulcers) in ats. The …
Role of growth factors in gastroduodenal protection and healing of peptic ulcers
SJ Konturek - Gastroenterology Clinics of North America, 1990 - Elsevier
Proliferation and growth of gastroduodenal mucosal cells represent important elements of
mucosal defense and any alterations in the balance between cell proliferation and cell loss …
mucosal defense and any alterations in the balance between cell proliferation and cell loss …
Effects of zincl-carnosine on gastric mucosal and cell damage caused by ethanol in rats: Correlation with endogenous prostaglandin E2
T Arakawa, H Satoh, A Nakamura, H Nebiki… - Digestive diseases and …, 1990 - Springer
The effects of zinc l-carnosine on ethanol-induced damage and the correlation of these
effects with endogenous prostaglandin E 2 were evaluated in rat gastric mucosa in vivo and …
effects with endogenous prostaglandin E 2 were evaluated in rat gastric mucosa in vivo and …