NOD-like receptors mediate homeostatic intestinal epithelial barrier function: promising therapeutic targets for inflammatory bowel disease

F Zhou, GD Zhang, Y Tan, SA Hu… - Therapeutic …, 2023 - journals.sagepub.com
Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory disease that
involves host genetics, the microbiome, and inflammatory responses. The current consensus …

[HTML][HTML] Treatment of ulcerative colitis with Wu-Mei-Wan by inhibiting intestinal inflammatory response and repairing damaged intestinal mucosa

S Yan, P Wang, H Wei, R Jia, M Zhen, Q Li, C Xue, J Li - Phytomedicine, 2022 - Elsevier
Abstract Background Wu-Mei-Wan (WMW), a traditional Chinese medicine, has been
applied in the treatment of gastrointestinal diseases with long-term diarrhea and …

Pharmacological effects of ginseng and ginsenosides on intestinal inflammation and the immune system

L Zhao, T Zhang, K Zhang - Frontiers in Immunology, 2024 - frontiersin.org
Intestinal inflammatory imbalance and immune dysfunction may lead to a spectrum of
intestinal diseases, such as inflammatory bowel disease (IBD) and gastrointestinal tumors …

Epimedin A ameliorates DNFB-induced allergic contact dermatitis in mice: Role of NF-κB/NLRP3-driven pyroptosis, Nrf2/HO-1 pathway, and inflammation modulation

MF Balaha, NJ Ahmed, ZS Almalki, AK Alahmari… - Life sciences, 2022 - Elsevier
Aims The present study aimed to investigate the potential of epimedin A to ameliorate DNFB-
induced allergic contact dermatitis (CD) and reveal its potential underlying mechanisms of …

Based on network pharmacology and molecular docking to explore the protective effect of Epimedii Folium extract on cisplatin-induced intestinal injury in mice

J Xia, JN Hu, Z Wang, EB Cai, S Ren… - Frontiers in …, 2022 - frontiersin.org
Background: Epimedii Folium, as a natural botanical medicine, has been reported to have
protective effects on intestinal diseases by modulating multiple signaling pathways. This …

[HTML][HTML] Combination of red ginseng and velvet antler extracts prevents skin damage by enhancing the antioxidant defense system and inhibiting MAPK/AP-1/NF-κB …

VL Truong, YJ Bae, JH Bang, WS Jeong - Journal of Ginseng Research, 2024 - Elsevier
Background Studies have reported that the combination of two or more therapeutic
compounds at certain ratios has more noticeable pharmaceutical properties than single …

[HTML][HTML] Restorative effects of Rg3-enriched Korean Red Ginseng and Persicaria tinctoria extract on oxazolone-induced ulcerative colitis in mice

HMA Ullah, E Saba, YY Lee, SB Hong, SH Hyun… - Journal of Ginseng …, 2022 - Elsevier
Background Ulcerative colitis (UC) is the large intestine disease that results in chronic
inflammation and ulcers in the colon. Rg3-enriched Korean Red Ginseng extract (Rg3-RGE) …

Wenshenyang recipe treats infertility through hormonal regulation and inflammatory responses revealed by transcriptome analysis and network pharmacology

L Xie, S Zhao, X Zhang, W Huang, L Qiao… - Frontiers in …, 2022 - frontiersin.org
The Wenshenyang recipe (WSYR) has the effect of treating infertility, but the mechanisms
underlying this activity have not been fully elucidated. In this study, network pharmacology …

The ginsenoside Rg2 downregulates MMP-1 expression in keratinocyte (HaCaT)-conditioned medium-treated human fibroblasts (Hs68)

S Oh, S Park, P Lee, YM Kim - Applied Biological Chemistry, 2023 - Springer
Keratinocytes exposed to UVB induce the production of cytokines, which activate fibroblasts
and increase the expression of matrix metalloproteinases (MMPs). The increased …

Duchesnea indica Extract Attenuates Coal Fly Ash‐Induced Inflammation in Murine Alveolar Macrophages through the NF‐Kappa B Pathway

HMA Ullah, YY Lee, SD Kim… - … and Alternative Medicine, 2021 - Wiley Online Library
Duchesnea indica is known as false strawberry, is found in East Asia, and has numerous
biological properties. The aim of this study was to investigate the anti‐inflammatory effect of …