Irritable bowel syndrome: a gut microbiota-related disorder?

Y Bhattarai, DA Muniz Pedrogo… - American Journal of …, 2017 - journals.physiology.org
Irritable bowel syndrome (IBS) is one of the most common gastrointestinal (GI) disorders.
Despite its prevalence, the pathophysiology of IBS is not well understood although multiple …

Targeted therapy of irritable bowel syndrome with anti-inflammatory cytokines

S Kumar, P Singh, A Kumar - Clinical Journal of Gastroenterology, 2022 - Springer
Irritable bowel syndrome (IBS) is a multifactorial disease of which infection, as well as
inflammation, has recently been considered as an important cause. Inflammation works as a …

The effect of glutamine supplementation on serum levels of some inflammatory factors, oxidative stress, and appetite in COVID-19 patients: a case–control study

M Mohajeri, E Horriatkhah, R Mohajery - Inflammopharmacology, 2021 - Springer
Background Malnutrition is seen in COVID-19 patients, and reducing malnutrition with
appropriate therapies may improve these patients' health. This case–control study aimed to …

[HTML][HTML] Fructo-oligosaccharide intensifies visceral hypersensitivity and intestinal inflammation in a stress-induced irritable bowel syndrome mouse model

BR Chen, LJ Du, HQ He, JJ Kim, Y Zhao… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To determine whether fructo-oligosaccharide (FOS) affects visceral sensitivity,
inflammation, and production of intestinal short-chain fatty acids (SCFA) in an irritable bowel …

Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via its antioxidant, anti‑inflammatory, and anti‑apoptotic activities

C Long, J Yang, H Yang, X Li… - Molecular Medicine …, 2016 - spandidos-publications.com
Abstract Ischemia/reperfusion (I/R)‑associated acute kidney injury is a major clinical problem
in both native and transplanted kidneys. Renal I/R, and subsequent renal injury, may be …

Up‐regulation of transient receptor potential vanilloid (TRPV) and down‐regulation of brain‐derived neurotrophic factor (BDNF) expression in patients with functional …

CKY Cheung, LL Lan, M Kyaw… - …, 2018 - Wiley Online Library
Background The role of immune activation in Functional Dyspepsia (FD) patients without
previous infection is unclear. We compare the gastric and circulating brain‐derived …

Systemic cytokines are elevated in a subset of patients with irritable bowel syndrome but largely unrelated to symptom characteristics

SMP Bennet, O Palsson, WE Whitehead… - …, 2018 - Wiley Online Library
Background Serum levels of pro‐inflammatory cytokines tend to be increased in irritable
bowel syndrome (IBS) patients, or subgroups thereof. Still, the link between cytokine levels …

Expression of inducible nitric oxide synthase in mast cells contributes to the regulation of inflammatory cytokines in irritable bowel syndrome with diarrhea

S An, G Zong, Z Wang, J Shi, H Du… - Neurogastroenterology & …, 2016 - Wiley Online Library
Background Nitric oxide (NO) and mast cells (MC s) are possibly involved in the
development of irritable bowel syndrome (IBS), but details on their role and interactions still …

Validation and Optimization of an Ex Vivo Assay of Intestinal Mucosal Biopsies in Crohn's Disease: Reflects Inflammation and Drug Effects

K Vadstrup, ED Galsgaard, J Gerwien… - PLoS …, 2016 - journals.plos.org
Crohn's disease (CD) is a chronic illness demanding better therapeutics. The marketed
biologics only benefit some patients or elicit diminishing effect over time. To complement the …

[HTML][HTML] Aquaporins 1, 3 and 8 expression and cytokines in irritable bowel syndrome rats' colon via cAMP-PKA pathway

G Chao, S Zhang - … Journal of Clinical and Experimental Pathology, 2018 - ncbi.nlm.nih.gov
Background: Irritable bowel syndrome (IBS) is one of the most common gastrointestinal (GI)
disorders. The cAMP-PKA pathway plays a key role in mediating cell responses to various …